ARG42094
anti-CRLS1 antibody
anti-CRLS1 antibody for IHC-Formalin-fixed paraffin-embedded sections,Western blot and Human
概述
| 产品描述 | Goat Polyclonal antibody recognizes CRLS1 |
|---|---|
| 反应物种 | Hu |
| 预测物种 | Ms, Rat, Cow, Dog, Pig |
| 应用 | IHC-P, WB |
| 特异性 | This antibody is expected to recognize both reported isoforms (NP_061968.1; NP_001120930.1). |
| 宿主 | Goat |
| 克隆 | Polyclonal |
| 同位型 | IgG |
| 靶点名称 | CRLS1 |
| 抗原物种 | Human |
| 抗原 | Synthetic peptide around the internal region of Human CRLS1. (C-RSALGSALDPLADK) (NP_061968.1; NP_001120930.1) |
| 偶联标记 | Un-conjugated |
| 別名 | CLS; CLS1; GCD10; C20orf155; dJ967N21.6; Cardiolipin synthase (CMP-forming); CLS; EC 2.7.8.41; Protein GCD10 homolog |
应用说明
| 应用建议 |
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| 应用说明 | WB: Recommend incubate at RT for 1h. IHC-P: Antigen Retrieval: Steam tissue section in Citrate buffer (pH 6.0). * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. |
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| 阳性对照 | HEK293 | ||||||
| 实际分子量 | ~ 33 kDa |
属性
| 形式 | Liquid |
|---|---|
| 纯化 | Affinity purified |
| 缓冲液 | Tris saline (pH 7.3), 0.02% Sodium azide and 0.5% BSA. |
| 抗菌剂 | 0.02% Sodium azide |
| 稳定剂 | 0.5% BSA |
| 浓度 | 0.5 mg/ml |
| 存放说明 | For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C or below. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
| 注意事项 | For laboratory research only, not for drug, diagnostic or other use. |
生物信息
| 数据库连接 |
Swiss-port # Q9UJA2 Human Cardiolipin synthase (CMP-forming) |
|---|---|
| 基因名称 | CRLS1 |
| 全名 | cardiolipin synthase 1 |
| 背景介绍 | This gene encodes a member of the CDP-alcohol phosphatidyltransferase class-I family of proteins. The encoded enzyme catalyzes the synthesis of cardiolipin, a phospholipid component of mitochondrial membranes that is critical for mitochondrial function. [provided by RefSeq, Apr 2016] |
| 生物功能 | Catalyzes the synthesis of cardiolipin (CL) (diphosphatidylglycerol) by specifically transferring a phosphatidyl group from CDP-diacylglycerol to phosphatidylglycerol (PG). CL is a key phospholipid in mitochondrial membranes and plays important roles in maintaining the functional integrity and dynamics of mitochondria under both optimal and stress conditions. [UniProt] |
| 细胞定位 | Mitochondrion inner membrane; Multi-pass membrane protein. [UniProt] |
| 预测分子量 | 33 kDa |
检测图片 (2) Click the Picture to Zoom In
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ARG42094 anti-CRLS1 antibody IHC-P image
Immunohistochemistry: Paraffin-embedded Human kidney tissue. Antigen Retrieval: Steam tissue section in Citrate buffer (pH 6.0). The tissue section was stained with ARG42094 anti-CRLS1 antibody at 5 µg/ml dilution.
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ARG42094 anti-CRLS1 antibody WB image
Western blot: 35 µg of HEK293 cell lysate (in RIPA buffer) stained with ARG42094 anti-CRLS1 antibody at 0.2 µg/ml dilution and incubated at RT for 1 hour.
