ARG59915
anti-CRCP antibody
anti-CRCP antibody for IHC-Formalin-fixed paraffin-embedded sections,Western blot and Human,Mouse,Rat
概述
| 产品描述 | Rabbit Polyclonal antibody recognizes CRCP |
|---|---|
| 反应物种 | Hu, Ms, Rat |
| 应用 | IHC-P, WB |
| 宿主 | Rabbit |
| 克隆 | Polyclonal |
| 同位型 | IgG |
| 靶点名称 | CRCP |
| 抗原物种 | Human |
| 抗原 | Recombinant fusion protein corresponding to aa. 1-115 of Human CRCP (NP_001035737.1). |
| 偶联标记 | Un-conjugated |
| 別名 | CGRPRCP; Calcitonin gene-related peptide-receptor component protein; RNA polymerase III subunit C9; RCP; RCP9; CGRP-receptor component protein; HsC17; CGRP-RCP; DNA-directed RNA polymerase III subunit RPC9 |
应用说明
| 应用建议 |
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| 应用说明 | * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. | ||||||
| 阳性对照 | Mouse testis and Jurkat | ||||||
| 实际分子量 | 17 kDa |
属性
| 形式 | Liquid |
|---|---|
| 纯化 | Affinity purified. |
| 缓冲液 | PBS (pH 7.3), 0.02% Sodium azide and 50% Glycerol. |
| 抗菌剂 | 0.02% Sodium azide |
| 稳定剂 | 50% Glycerol |
| 存放说明 | For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
| 注意事项 | For laboratory research only, not for drug, diagnostic or other use. |
生物信息
| 数据库连接 | |
|---|---|
| 基因名称 | CRCP |
| 全名 | CGRP receptor component |
| 背景介绍 | This gene encodes a membrane protein that functions as part of a receptor complex for a small neuropeptide that increases intracellular cAMP levels. Alternate transcriptional splice variants, encoding different isoforms, have been characterized. [provided by RefSeq, Jul 2008] |
| 生物功能 | DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Specific peripheric component of RNA polymerase III which synthesizes small RNAs, such as 5S rRNA and tRNAs. Plays a key role in sensing and limiting infection by intracellular bacteria and DNA viruses. Acts as nuclear and cytosolic DNA sensor involved in innate immune response. Can sense non-self dsDNA that serves as template for transcription into dsRNA. The non-self RNA polymerase III transcripts induce type I interferon and NF- Kappa-B through the RIG-I pathway (By similarity). Accessory protein for the calcitonin gene-related peptide (CGRP) receptor. It modulates CGRP responsiveness in a variety of tissues. [UniProt] |
| 细胞定位 | Nucleus. Cell membrane; Peripheral membrane protein; Cytoplasmic side. [UniProt] |
| 预测分子量 | 17 kDa |
检测图片 (1) Click the Picture to Zoom In
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ARG59915 anti-CRCP antibody WB image
Western blot: 25 µg of Mouse testis and Jurkat cell lysates stained with ARG59915 anti-CRCP antibody at 1:3000 dilution.
