概述

产品描述	Rabbit Polyclonal antibody recognizes CPI-17
反应物种	Hu, Ms, Rat
应用	IP, WB
宿主	Rabbit
克隆	Polyclonal
同位型	IgG
靶点名称	CPI-17
抗原物种	Human
抗原	Synthetic peptide of Human CPI-17.
偶联标记	Un-conjugated
別名	CPI-17; Protein kinase C-potentiated inhibitor protein of 17 kDa; CPI17; 17 kDa PKC-potentiated inhibitory protein of PP1; PPP1INL; Protein phosphatase 1 regulatory subunit 14A

应用说明

应用建议	应用 推荐稀释比 IP 1:30 WB 1:500 - 1:2000
应用说明	* The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist.
阳性对照	MCF7
实际分子量	~ 20 kDa

属性

形式	Liquid
纯化	Affinity purified.
缓冲液	PBS (pH 7.4), 150 mM NaCl, 0.02% Sodium azide and 50% Glycerol.
抗菌剂	0.02% Sodium azide
稳定剂	50% Glycerol
存放说明	For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use.
注意事项	For laboratory research only, not for drug, diagnostic or other use.

生物信息

数据库连接	GeneID: 114004 Rat PPP1R14A GeneID: 68458 Mouse PPP1R14A GeneID: 94274 Human PPP1R14A Swiss-port # Q91VC7 Mouse Protein phosphatase 1 regulatory subunit 14A Swiss-port # Q96A00 Human Protein phosphatase 1 regulatory subunit 14A Swiss-port # Q99MC0 Rat Protein phosphatase 1 regulatory subunit 14A More
基因名称	PPP1R14A
全名	protein phosphatase 1, regulatory (inhibitor) subunit 14A
背景介绍	The protein encoded by this gene belongs to the protein phosphatase 1 (PP1) inhibitor family. This protein is an inhibitor of smooth muscle myosin phosphatase, and has higher inhibitory activity when phosphorylated. Inhibition of myosin phosphatase leads to increased myosin phosphorylation and enhanced smooth muscle contraction. Alternatively spliced transcript variants encoding different isoforms have been noted for this gene. [provided by RefSeq, Sep 2011]
生物功能	Inhibitor of PPP1CA. Has over 1000-fold higher inhibitory activity when phosphorylated, creating a molecular switch for regulating the phosphorylation status of PPP1CA substrates and smooth muscle contraction. [UniProt]
细胞定位	Cytoplasm. [UniProt]
预测分子量	17 kDa

检测图片 (1) Click the Picture to Zoom In