ARG58383
anti-COX6A1 antibody
anti-COX6A1 antibody for ICC/IF,IHC-Formalin-fixed paraffin-embedded sections,Western blot and Human,Mouse,Rat
概述
| 产品描述 | Rabbit Polyclonal antibody recognizes COX6A1 |
|---|---|
| 反应物种 | Hu, Ms, Rat |
| 应用 | ICC/IF, IHC-P, WB |
| 宿主 | Rabbit |
| 克隆 | Polyclonal |
| 同位型 | IgG |
| 靶点名称 | COX6A1 |
| 抗原物种 | Human |
| 抗原 | Recombinant fusion protein corresponding to aa. 25-109 of Human COX6A1 (NP_004364.2). |
| 偶联标记 | Un-conjugated |
| 別名 | COX6AL; Cytochrome c oxidase subunit VIA-liver; Cytochrome c oxidase subunit 6A1, mitochondrial; CMTRID; COX VIa-L; COX6A; Cytochrome c oxidase polypeptide VIa-liver |
应用说明
| 应用建议 |
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| 应用说明 | * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. | ||||||||
| 阳性对照 | Rat liver | ||||||||
| 实际分子量 | 12 kDa |
属性
| 形式 | Liquid |
|---|---|
| 纯化 | Affinity purified. |
| 缓冲液 | PBS (pH 7.3), 0.02% Sodium azide and 50% Glycerol. |
| 抗菌剂 | 0.02% Sodium azide |
| 稳定剂 | 50% Glycerol |
| 存放说明 | For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
| 注意事项 | For laboratory research only, not for drug, diagnostic or other use. |
生物信息
| 数据库连接 | |
|---|---|
| 基因名称 | COX6A1 |
| 全名 | cytochrome c oxidase subunit VIa polypeptide 1 |
| 背景介绍 | Cytochrome c oxidase (COX), the terminal enzyme of the mitochondrial respiratory chain, catalyzes the electron transfer from reduced cytochrome c to oxygen. It is a heteromeric complex consisting of 3 catalytic subunits encoded by mitochondrial genes and multiple structural subunits encoded by nuclear genes. The mitochondrially-encoded subunits function in the electron transfer and the nuclear-encoded subunits may function in the regulation and assembly of the complex. This nuclear gene encodes polypeptide 1 (liver isoform) of subunit VIa, and polypeptide 1 is found in all non-muscle tissues. Polypeptide 2 (heart/muscle isoform) of subunit VIa is encoded by a different gene, and is present only in striated muscles. These two polypeptides share 66% amino acid sequence identity. It has been reported that there may be several pseudogenes on chromosomes 1, 6, 7q21, 7q31-32 and 12. However, only one pseudogene (COX6A1P) on chromosome 1p31.1 has been documented. [provided by RefSeq, Jul 2008] |
| 生物功能 | This protein is one of the nuclear-coded polypeptide chains of cytochrome c oxidase, the terminal oxidase in mitochondrial electron transport. [UniProt] |
| 细胞定位 | Mitochondrion inner membrane. [UniProt] |
| 预测分子量 | 12 kDa |
检测图片 (2) Click the Picture to Zoom In
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ARG58383 anti-COX6A1 antibody IHC-P image
Immunohistochemistry: Paraffin-embedded Mouse kidney stained with ARG58383 anti-COX6A1 antibody at 1:100 dilution.
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ARG58383 anti-COX6A1 antibody WB image
Western blot: 25 µg of Rat liver lysate stained with ARG58383 anti-COX6A1 antibody at 1:1000 dilution.
