ARG42480

anti-COPG2 antibody

anti-COPG2 antibody for ICC/IF,IHC-Formalin-fixed paraffin-embedded sections,Western blot and Human,Mouse,Rat

概述

产品描述 Rabbit Polyclonal antibody recognizes COPG2
反应物种 Hu, Ms, Rat
应用 ICC/IF, IHC-P, WB
宿主 Rabbit
克隆 Polyclonal
同位型 IgG
靶点名称 COPG2
抗原物种 Human
抗原 Recombinant fusion protein corresponding to aa. 542-871 of Human COPG2 (NP_036265.3).
偶联标记 Un-conjugated
別名 Gamma-2-COP; Gamma-2-coat protein; gamma-2-COP; Coatomer subunit gamma-2; 2-COP

应用说明

应用建议
应用 推荐稀释比
ICC/IF1:50 - 1:200
IHC-P1:50 - 1:200
WB1:500 - 1:2000
应用说明 * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist.
阳性对照 OVCAR3
实际分子量 ~ 100 kDa

属性

形式 Liquid
纯化 Affinity purified.
缓冲液 PBS (pH 7.3), 0.02% Sodium azide and 50% Glycerol.
抗菌剂 0.02% Sodium azide
稳定剂 50% Glycerol
存放说明 For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use.
注意事项 For laboratory research only, not for drug, diagnostic or other use.

生物信息

数据库连接

GeneID: 26958 Human COPG2

GeneID: 54160 Mouse COPG2

Swiss-port # Q9QXK3 Mouse Coatomer subunit gamma-2

Swiss-port # Q9UBF2 Human Coatomer subunit gamma-2

基因名称 COPG2
全名 coatomer protein complex, subunit gamma 2
生物功能 The coatomer is a cytosolic protein complex that binds to dilysine motifs and reversibly associates with Golgi non-clathrin-coated vesicles, which further mediate biosynthetic protein transport from the ER, via the Golgi up to the trans Golgi network. Coatomer complex is required for budding from Golgi membranes, and is essential for the retrograde Golgi-to-ER transport of dilysine-tagged proteins. In mammals, the coatomer can only be recruited by membranes associated to ADP-ribosylation factors (ARFs), which are small GTP-binding proteins; the complex also influences the Golgi structural integrity, as well as the processing, activity, and endocytic recycling of LDL receptors (By similarity). [UniProt]
细胞定位 Cytoplasm, cytosol. Golgi apparatus membrane; Peripheral membrane protein; Cytoplasmic side. Cytoplasmic vesicle, COPI-coated vesicle membrane; Peripheral membrane protein; Cytoplasmic side. Note=The coatomer is cytoplasmic or polymerized on the cytoplasmic side of the Golgi, as well as on the vesicles/buds originating from it. Tends to be more abundant in the trans-Golgi network compared to the cis-Golgi. [UniProt]
预测分子量 98 kDa

检测图片 (2) Click the Picture to Zoom In

  • ARG42480 anti-COPG2 antibody ICC/IF image

    Immunofluorescence: U2OS cells stained with ARG42480 anti-COPG2 antibody at 1:100 dilution.

  • ARG42480 anti-COPG2 antibody WB image

    Western blot: 25 µg of OVCAR3 cell lysate stained with ARG42480 anti-COPG2 antibody at 1:1000 dilution.