ARG52246
anti-COBRA1 antibody [F7E4]
anti-COBRA1 antibody [F7E4] for Western blot and Human,Mouse,Rat
Gene Regulation antibody
概述
| 产品描述 | Mouse Monoclonal antibody [F7E4] recognizes COBRA1 |
|---|---|
| 反应物种 | Hu, Ms, Rat |
| 应用 | WB |
| 宿主 | Mouse |
| 克隆 | Monoclonal |
| 克隆号 | F7E4 |
| 同位型 | IgG1 |
| 靶点名称 | COBRA1 |
| 抗原物种 | Human |
| 抗原 | Recombinant full length human COBRA1 purified from E. coli |
| 偶联标记 | Un-conjugated |
| 別名 | COBRA1; Negative elongation factor B; NELF-B; Cofactor of BRCA1 |
应用说明
| 应用建议 |
|
||||
|---|---|---|---|---|---|
| 应用说明 | Specific for the ~62k COBRA1 protein in Western blots of neonatal Rat brain lysate. * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. |
属性
| 形式 | Liquid |
|---|---|
| 纯化 | Protein G purified |
| 缓冲液 | 10 mM HEPES (pH 7.5), 150 mM NaCl, 0.1 mg/ml BSA and 50% Glycerol |
| 稳定剂 | 0.1 mg/ml BSA, 50% Glycerol |
| 存放说明 | For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
| 注意事项 | For laboratory research only, not for drug, diagnostic or other use. |
生物信息
| 数据库连接 | |
|---|---|
| 基因名称 | COBRA1 |
| 全名 | negative elongation factor complex member B |
| 背景介绍 | COBRA1 (cofactor of BRCA1) also known as NELF-B, is an essential component of the negative elongation factor (NELF) complex. COBRA1 has been shown to directly bind estrogen receptor alpha (ERα) and repress ERα-mediated transcription (Aiyar SE et al., 2004). COBRA1 has also been demonstrated to interact with c-Jun and c-Fos suggesting a role in modulation of the AP-1 pathway and therefore may be important in cell proliferation, differentiation, apoptosis and oncogeneis (Zhong H et al., 2004) |
| 研究领域 | Gene Regulation antibody |
| 预测分子量 | 66 kDa |
检测图片 (1) Click the Picture to Zoom In
-
ARG52246 anti-COBRA1 antibody [F7E4] WB image
Western blot: Rat neonatal brain lysate showing specific immunolabeling of the ~62 kDa COBRA1 protein stained with ARG52246 anti-COBRA1 antibody [F7E4].
