ARG41113
anti-CNOT8 antibody
anti-CNOT8 antibody for Western blot and Human,Mouse
概述
| 产品描述 | Rabbit Polyclonal antibody recognizes CNOT8 |
|---|---|
| 反应物种 | Hu, Ms |
| 应用 | WB |
| 宿主 | Rabbit |
| 克隆 | Polyclonal |
| 同位型 | IgG |
| 靶点名称 | CNOT8 |
| 抗原物种 | Human |
| 抗原 | Recombinant fusion protein corresponding to aa. 1-292 of Human CNOT8 (NP_004770.4). |
| 偶联标记 | Un-conjugated |
| 別名 | CCR4-associated factor 8; Caf1b; CAF1-like protein; CALIF; CAF2; CAF1; POP2; hCAF1; EC 3.1.13.4; CCR4-NOT transcription complex subunit 8; CALIFp |
应用说明
| 应用建议 |
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|---|---|---|---|---|---|
| 应用说明 | * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. | ||||
| 阳性对照 | Mouse liver | ||||
| 实际分子量 | 34 kDa |
属性
| 形式 | Liquid |
|---|---|
| 纯化 | Affinity purified. |
| 缓冲液 | PBS (pH 7.3), 0.02% Sodium azide and 50% Glycerol. |
| 抗菌剂 | 0.02% Sodium azide |
| 稳定剂 | 50% Glycerol |
| 存放说明 | For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
| 注意事项 | For laboratory research only, not for drug, diagnostic or other use. |
生物信息
| 数据库连接 |
Swiss-port # Q9D8X5 Mouse CCR4-NOT transcription complex subunit 8 Swiss-port # Q9UFF9 Human CCR4-NOT transcription complex subunit 8 |
|---|---|
| 基因名称 | CNOT8 |
| 全名 | CCR4-NOT transcription complex, subunit 8 |
| 生物功能 | Has 3'-5' poly(A) exoribonuclease activity for synthetic poly(A) RNA substrate. Its function seems to be partially redundant with that of CNOT7. Catalytic component of the CCR4-NOT complex which is linked to various cellular processes including bulk mRNA degradation, miRNA-mediated repression, translational repression during translational initiation and general transcription regulation. During miRNA-mediated repression the complex seems also to act as translational repressor during translational initiation. Additional complex functions may be a consequence of its influence on mRNA expression. Associates with members of the BTG family such as TOB1 and BTG2 and is required for their anti-proliferative activity. [UniProt] |
| 细胞定位 | Cytoplasm. Nucleus. [UniProt] |
| 预测分子量 | 34 kDa |
检测图片 (1) Click the Picture to Zoom In
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ARG41113 anti-CNOT8 antibody WB image
Western blot: 25 µg of Mouse liver lysate stained with ARG41113 anti-CNOT8 antibody at 1:1000 dilution.
