ARG55215
anti-CNOT4 antibody [343CT14.6.5]
anti-CNOT4 antibody [343CT14.6.5] for Western blot and Human,Mouse
Cell Biology and Cellular Response antibody; Gene Regulation antibody
概述
| 产品描述 | Mouse Monoclonal antibody recognizes CNOT4 |
|---|---|
| 反应物种 | Hu, Ms |
| 应用 | WB |
| 宿主 | Mouse |
| 克隆 | Monoclonal |
| 克隆号 | 343CT14.6.5 |
| 同位型 | IgG2a, kappa |
| 靶点名称 | CNOT4 |
| 抗原物种 | Human |
| 抗原 | Recombinant protein of Human CNOT4 (Swiss: O95628). |
| 偶联标记 | Un-conjugated |
| 別名 | CLONE243; NOT4; NOT4H; EC 6.3.2.-; CCR4-associated factor 4; Potential transcriptional repressor NOT4Hp; CCR4-NOT transcription complex subunit 4; E3 ubiquitin-protein ligase CNOT4 |
应用说明
| 应用建议 |
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|---|---|---|---|---|---|
| 应用说明 | * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. | ||||
| 阳性对照 | Mouse heart |
属性
| 形式 | Liquid |
|---|---|
| 纯化 | Purification with Protein G. |
| 缓冲液 | PBS and 0.09% (W/V) Sodium azide |
| 抗菌剂 | 0.09% (W/V) Sodium azide |
| 存放说明 | For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C or below. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
| 注意事项 | For laboratory research only, not for drug, diagnostic or other use. |
生物信息
| 数据库连接 |
Swiss-port # O95628 Human CCR4-NOT transcription complex subunit 4 Swiss-port # Q8BT14 Mouse CCR4-NOT transcription complex subunit 4 |
|---|---|
| 基因名称 | CNOT4 |
| 全名 | CCR4-NOT transcription complex, subunit 4 |
| 背景介绍 | The protein encoded by this gene is a subunit of the CCR4-NOT complex, a global transcriptional regulator. The encoded protein interacts with CNOT1 and has E3 ubiquitin ligase activity. Several transcript variants encoding different isoforms have been found for this gene.[provided by RefSeq, Jul 2010] |
| 生物功能 | Has E3 ubiquitin ligase activity. Involved in activation of the JAK/STAT pathway. [UniProt] |
| 细胞定位 | Cytoplasm. Nucleus |
| 研究领域 | Cell Biology and Cellular Response antibody; Gene Regulation antibody |
| 预测分子量 | 64 kDa |
| 翻译后修饰 | Autoubiquitinated. |
检测图片 (1) Click the Picture to Zoom In
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ARG55215 anti-CNOT4 antibody WB image
Western blot: 35 µg of Mouse heart lysate stained with ARG55215 anti-CNOT4 antibody.
