概述

产品描述	Rabbit Polyclonal antibody recognizes CMPK2
反应物种	Hu, Ms, Rat
应用	WB
宿主	Rabbit
克隆	Polyclonal
同位型	IgG
靶点名称	CMPK2
抗原物种	Human
抗原	A 19 amino acid synthetic peptide within aa. 370 - 420 of human CMPK2.
偶联标记	Un-conjugated
別名	CMPK2; TYKi; EC 2.7.4.14; UMP-CMPK2; Nucleoside-diphosphate kinase; UMP-CMP kinase 2, mitochondrial; TMPK2; EC 2.7.4.6

应用说明

应用建议	应用 推荐稀释比 WB Assay-dependent
应用说明	* The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist.

属性

纯化	Affinity chromatography purified
缓冲液	PBS and 0.02% Sodium azide.
抗菌剂	0.02% Sodium azide
浓度	1 mg/ml
存放说明	For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use.
注意事项	For laboratory research only, not for drug, diagnostic or other use.

生物信息

数据库连接	GeneID: 129607 Human CMPK2 GeneID: 22169 Mouse CMPK2 Swiss-port # Q3U5Q7 Mouse UMP-CMP kinase 2, mitochondrial Swiss-port # Q5EBM0 Human UMP-CMP kinase 2, mitochondrial
基因名称	CMPK2
全名	cytidine monophosphate (UMP-CMP) kinase 2, mitochondrial
背景介绍	This gene encodes one of the enzymes in the nucleotide synthesis salvage pathway that may participate in terminal differentiation of monocytic cells. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Feb 2012]
生物功能	May participate in dUTP and dCTP synthesis in mitochondria. Is able to phosphorylate dUMP, dCMP, CMP, UMP and monophosphates of the pyrimidine nucleoside analogs ddC, dFdC, araC, BVDU and FdUrd with ATP as phosphate donor. Efficacy is highest for dUMP followed by dCMP; CMP and UMP are poor substrates. May be involved in mtDNA depletion caused by long term treatment with ddC or other pyrimidine analogs. Also displays broad nucleoside diphosphate kinase activity. [UniProt]
细胞定位	Mitochondrion. [UniProt]
预测分子量	49.5 kDa

检测图片 (1) Click the Picture to Zoom In