ARG45964
anti-CLEC12A antibody [50C1]
anti-CLEC12A antibody [50C1] for Flow cytometry and Human
概述
产品描述 | Mouse Monoclonal antibody [50C1] recognizes CLEC12A |
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反应物种 | Hu |
应用 | FACS |
宿主 | Mouse |
克隆 | Monoclonal |
克隆号 | 50C1 |
同位型 | IgG2a |
靶点名称 | CLEC12A |
抗原物种 | Human |
抗原 | 293T cells expressing human CLEC12A |
別名 | CLEC12A; C-type lectin domain family 12, member A; Dendritic cell-associated lectin 2; C-type lectin domain family 12 member A; Myeloid inhibitory C-type lectin-like receptor; DCAL-2; C-type lectin-like molecule 1; MICL; CD371; CLL-1; CLL1 |
应用说明
应用建议 |
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应用说明 | * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. |
属性
形式 | Liquid |
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纯化 | Protein-A affinity chromatography |
缓冲液 | PBS and 15 mM Sodium azide. |
抗菌剂 | 15 mM Sodium azide |
浓度 | 1 mg/ml |
存放说明 | For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C or below. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
注意事项 | For laboratory research only, not for drug, diagnostic or other use. |
生物信息
数据库连接 |
Swiss-port # Q5QGZ9 Human C-type lectin domain family 12 member A |
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基因名称 | CLEC12A |
全名 | C-type lectin domain family 12, member A |
背景介绍 | This gene encodes a member of the C-type lectin/C-type lectin-like domain (CTL/CTLD) superfamily. Members of this family share a common protein fold and have diverse functions, such as cell adhesion, cell-cell signaling, glycoprotein turnover, and roles in inflammation and immune response. The protein encoded by this gene is a negative regulator of granulocyte and monocyte function. Several alternatively spliced transcript variants of this gene have been described, but the full-length nature of some of these variants has not been determined. This gene is closely linked to other CTL/CTLD superfamily members in the natural killer gene complex region on chromosome 12p13. [provided by RefSeq, May 2011] |
生物功能 | Cell surface receptor that modulates signaling cascades and mediates tyrosine phosphorylation of target MAP kinases. [UniProt] |
细胞定位 | Cell membrane; Single-pass type II membrane protein. Note=Ligand binding leads to internalization. [UniProt] |
翻译后修饰 | Highly N-glycosylated. Glycosylation varies between cell types. [UniProt] |
检测图片 (2) Click the Picture to Zoom In
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ARG45964 anti-CLEC12A antibody [50C1] FACS image
Flow Cytometry: Human peripheral whole blood stained with ARG45964 anti-CLEC12A antibody [50C1] at 1.67 μg/ml dilution.
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ARG45964 anti-CLEC12A antibody [50C1] FACS image
Flow Cytometry: Human peripheral whole blood stained with ARG45964 anti-CLEC12A antibody [50C1] at 1.67 μg/ml dilution.