ARG45964

anti-CLEC12A antibody [50C1]

anti-CLEC12A antibody [50C1] for Flow cytometry and Human

概述

产品描述 Mouse Monoclonal antibody [50C1] recognizes CLEC12A
反应物种 Hu
应用 FACS
宿主 Mouse
克隆 Monoclonal
克隆号 50C1
同位型 IgG2a
靶点名称 CLEC12A
抗原物种 Human
抗原 293T cells expressing human CLEC12A
別名 CLEC12A; C-type lectin domain family 12, member A; Dendritic cell-associated lectin 2; C-type lectin domain family 12 member A; Myeloid inhibitory C-type lectin-like receptor; DCAL-2; C-type lectin-like molecule 1; MICL; CD371; CLL-1; CLL1

应用说明

应用建议
应用 推荐稀释比
FACS1-5 μg/ml
应用说明 * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist.

属性

形式 Liquid
纯化 Protein-A affinity chromatography
缓冲液 PBS and 15 mM Sodium azide.
抗菌剂 15 mM Sodium azide
浓度 1 mg/ml
存放说明 For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C or below. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use.
注意事项 For laboratory research only, not for drug, diagnostic or other use.

生物信息

数据库连接

GeneID: 160364 Human CLEC12A

Swiss-port # Q5QGZ9 Human C-type lectin domain family 12 member A

基因名称 CLEC12A
全名 C-type lectin domain family 12, member A
背景介绍 This gene encodes a member of the C-type lectin/C-type lectin-like domain (CTL/CTLD) superfamily. Members of this family share a common protein fold and have diverse functions, such as cell adhesion, cell-cell signaling, glycoprotein turnover, and roles in inflammation and immune response. The protein encoded by this gene is a negative regulator of granulocyte and monocyte function. Several alternatively spliced transcript variants of this gene have been described, but the full-length nature of some of these variants has not been determined. This gene is closely linked to other CTL/CTLD superfamily members in the natural killer gene complex region on chromosome 12p13. [provided by RefSeq, May 2011]
生物功能 Cell surface receptor that modulates signaling cascades and mediates tyrosine phosphorylation of target MAP kinases. [UniProt]
细胞定位 Cell membrane; Single-pass type II membrane protein. Note=Ligand binding leads to internalization. [UniProt]
翻译后修饰 Highly N-glycosylated. Glycosylation varies between cell types. [UniProt]

检测图片 (2) Click the Picture to Zoom In

  • ARG45964 anti-CLEC12A antibody [50C1] FACS image

    Flow Cytometry: Human peripheral whole blood stained with ARG45964 anti-CLEC12A antibody [50C1] at 1.67 μg/ml dilution.

  • ARG45964 anti-CLEC12A antibody [50C1] FACS image

    Flow Cytometry: Human peripheral whole blood stained with ARG45964 anti-CLEC12A antibody [50C1] at 1.67 μg/ml dilution.