ARG63785

anti-CLCA1 antibody

anti-CLCA1 antibody for Western blot and Human

Signaling Transduction antibody

概述

产品描述 Goat Polyclonal antibody recognizes CLCA1
反应物种 Hu
应用 WB
特异性 No cross-reactivity expected with CLCA2 and 3.
宿主 Goat
克隆 Polyclonal
同位型 IgG
靶点名称 CLCA1
抗原物种 Human
抗原 C-TVTSKTNKDTSK
偶联标记 Un-conjugated
別名 hCLCA1; CACC1; Calcium-activated chloride channel regulator 1; Calcium-activated chloride channel family member 1; CaCC-1; Calcium-activated chloride channel protein 1; EC 3.4.-.-; GOB5; CACC; CLCRG1; hCaCC-1

应用说明

应用建议
应用 推荐稀释比
WB1 - 3 µg/ml
应用说明 WB: Recommend incubate at RT for 1h.
* The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist.

属性

形式 Liquid
纯化 Purified from goat serum by antigen affinity chromatography.
缓冲液 Tris saline (pH 7.3), 0.02% Sodium azide and 0.5% BSA.
抗菌剂 0.02% Sodium azide
稳定剂 0.5% BSA
浓度 0.5 mg/ml
存放说明 For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C or below. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use.
注意事项 For laboratory research only, not for drug, diagnostic or other use.

生物信息

数据库连接

GeneID: 1179 Human CLCA1

Swiss-port # A8K7I4 Human Calcium-activated chloride channel regulator 1

背景介绍 This gene encodes a member of the calcium sensitive chloride conductance protein family. To date, all members of this gene family map to the same region on chromosome 1p31-p22 and share a high degree of homology in size, sequence, and predicted structure, but differ significantly in their tissue distributions. The encoded protein is expressed as a precursor protein that is processed into two cell-surface-associated subunits, although the site at which the precursor is cleaved has not been precisely determined. The encoded protein may be involved in mediating calcium-activated chloride conductance in the intestine. [provided by RefSeq, Jul 2008]
研究领域 Signaling Transduction antibody
预测分子量 100 kDa
翻译后修饰 Glycosylated.
The 125-kDa product is autoproteolytically processed by the metalloprotease domain and yields to two cell-surface-associated subunits, a 90-kDa protein and a group of 37-to 41-kDa proteins. The cleavage is necessary for calcium-activated chloride channel (CaCC) activation activity.

检测图片 (1) Click the Picture to Zoom In

  • ARG63785 anti-CLCA1 antibody WB image

    Western Blot: Human Duodenum lysate (35 µg protein in RIPA buffer) stained with ARG63785 anti-CLCA1 antibody at 1 µg/ml dilution.