ARG57764
anti-CKMT2 antibody
anti-CKMT2 antibody for IHC-Formalin-fixed paraffin-embedded sections,Western blot and Human
概述
| 产品描述 | Rabbit Polyclonal antibody recognizes CKMT2 |
|---|---|
| 反应物种 | Hu |
| 预测物种 | Ms |
| 应用 | IHC-P, WB |
| 宿主 | Rabbit |
| 克隆 | Polyclonal |
| 同位型 | IgG |
| 靶点名称 | CKMT2 |
| 抗原物种 | Human |
| 抗原 | Synthetic peptide corresponding a region of Human CKMT2. |
| 偶联标记 | Un-conjugated |
| 別名 | EC 2.7.3.2; S-MtCK; Basic-type mitochondrial creatine kinase; Creatine kinase S-type, mitochondrial; Mib-CK; Sarcomeric mitochondrial creatine kinase; SMTCK |
应用说明
| 应用建议 |
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| 应用说明 | * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. | ||||||
| 阳性对照 | Jurkat cell lysate. | ||||||
| 实际分子量 | ~ 46 kDa |
属性
| 形式 | Liquid |
|---|---|
| 纯化 | Purification with Protein A. |
| 缓冲液 | PBS and 2% Sucrose. |
| 稳定剂 | 2% Sucrose |
| 浓度 | 1 mg/ml |
| 存放说明 | For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C or below. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
| 注意事项 | For laboratory research only, not for drug, diagnostic or other use. |
生物信息
| 数据库连接 |
Swiss-port # P17540 Human Creatine kinase S-type, mitochondrial |
|---|---|
| 基因名称 | CKMT2 |
| 全名 | creatine kinase, mitochondrial 2 (sarcomeric) |
| 背景介绍 | Mitochondrial creatine kinase (MtCK) is responsible for the transfer of high energy phosphate from mitochondria to the cytosolic carrier, creatine. It belongs to the creatine kinase isoenzyme family. It exists as two isoenzymes, sarcomeric MtCK and ubiquitous MtCK, encoded by separate genes. Mitochondrial creatine kinase occurs in two different oligomeric forms: dimers and octamers, in contrast to the exclusively dimeric cytosolic creatine kinase isoenzymes. Sarcomeric mitochondrial creatine kinase has 80% homology with the coding exons of ubiquitous mitochondrial creatine kinase. This gene contains sequences homologous to several motifs that are shared among some nuclear genes encoding mitochondrial proteins and thus may be essential for the coordinated activation of these genes during mitochondrial biogenesis. Three transcript variants encoding the same protein have been found for this gene. [provided by RefSeq, Jul 2008] |
| 生物功能 | Reversibly catalyzes the transfer of phosphate between ATP and various phosphogens (e.g. creatine phosphate). Creatine kinase isoenzymes play a central role in energy transduction in tissues with large, fluctuating energy demands, such as skeletal muscle, heart, brain and spermatozoa. [UniProt] |
| 预测分子量 | 48 kDa |
检测图片 (2) Click the Picture to Zoom In
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ARG57764 anti-CKMT2 antibody IHC-P image
Immunohistochemistry: Paraffin-embedded Human skeletal muscle stained with ARG57764 anti-CKMT2 antibody.
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ARG57764 anti-CKMT2 antibody WB image
Western blot: Jurkat cell lysate stained with ARG57764 anti-CKMT2 antibody at 1.25 µg/ml dilution.
