概述

产品描述	Rabbit Polyclonal antibody recognizes CKAP5
反应物种	Hu, Ms, Rat
应用	ICC/IF, IP, WB
宿主	Rabbit
克隆	Polyclonal
同位型	IgG
靶点名称	CKAP5
抗原物种	Human
抗原	Recombinant protein of Human CKAP5.
偶联标记	Un-conjugated
別名	Colonic and hepatic tumor overexpressed gene protein; TOGp; MSPS; Ch-TOG; Cytoskeleton-associated protein 5; CHTOG; TOG; ch-TOG

应用说明

应用建议	应用 推荐稀释比 ICC/IF 1:50 - 1:200 IP Assay-dependent WB 1:500 - 1:2000
应用说明	* The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist.
阳性对照	HT-29

属性

形式	Liquid
纯化	Affinity purification with immunogen.
缓冲液	PBS (pH 7.3), 0.02% Sodium azide and 50% Glycerol.
抗菌剂	0.02% Sodium azide
稳定剂	50% Glycerol
存放说明	For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use.
注意事项	For laboratory research only, not for drug, diagnostic or other use.

生物信息

数据库连接	GeneID: 75786 Mouse CKAP5 GeneID: 9793 Human CKAP5 Swiss-port # A2AGT5 Mouse Cytoskeleton-associated protein 5 Swiss-port # Q14008 Human Cytoskeleton-associated protein 5
基因名称	CKAP5
全名	cytoskeleton associated protein 5
背景介绍	This gene encodes a cytoskeleton-associated protein which belongs to the TOG/XMAP215 family. The N-terminal half of this protein contains a microtubule-binding domain and the C-terminal half contains a KXGS motif for binding tubulin dimers. This protein has two distinct roles in spindle formation; it protects kinetochore microtubules from depolymerization and plays an essential role in centrosomal microtubule assembly. This protein may be necessary for the proper interaction of microtubules with the cell cortex for directional cell movement. It also plays a role in translation of the myelin basic protein (MBP) mRNA by interacting with heterogeneous nuclear ribonucleoprotein (hnRNP) A2, which associates with MBP. Alternatively spliced transcript variants encoding different isoforms have been identified. [provided by RefSeq, Aug 2011]
生物功能	Binds to the plus end of microtubules and regulates microtubule dynamics and microtubule organization. Promotes cytoplasmic microtubule nucleation and elongation. Plays a major role in organizing spindle poles. [UniProt]
预测分子量	225 kDa

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