概述

产品描述	Rabbit Polyclonal antibody recognizes CISD2
反应物种	Hu, Ms, Rat
应用	IHC-P, WB
宿主	Rabbit
克隆	Polyclonal
同位型	IgG
靶点名称	CISD2
抗原物种	Human
抗原	Recombinant protein of Human CISD2.
偶联标记	Un-conjugated
別名	MitoNEET-related 1 protein; Miner1; ERIS; Endoplasmic reticulum intermembrane small protein; CDGSH iron-sulfur domain-containing protein 2; Nutrient-deprivation autophagy factor-1; WFS2; NAF-1; ZCD2

应用说明

应用建议	应用 推荐稀释比 IHC-P 1:50 - 1:200 WB 1:500 - 1:2000
应用说明	* The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist.
阳性对照	A549

属性

形式	Liquid
纯化	Affinity purification with immunogen.
缓冲液	PBS (pH 7.3), 0.02% Sodium azide and 50% Glycerol.
抗菌剂	0.02% Sodium azide
稳定剂	50% Glycerol
存放说明	For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use.
注意事项	For laboratory research only, not for drug, diagnostic or other use.

生物信息

数据库连接	GeneID: 493856 Human CISD2 GeneID: 67006 Mouse CISD2 Swiss-port # Q8N5K1 Human CDGSH iron-sulfur domain-containing protein 2 Swiss-port # Q9CQB5 Mouse CDGSH iron-sulfur domain-containing protein 2
基因名称	CISD2
全名	CDGSH iron sulfur domain 2
背景介绍	The protein encoded by this gene is a zinc finger protein that localizes to the endoplasmic reticulum. The encoded protein binds an iron/sulfur cluster and may be involved in calcium homeostasis. Defects in this gene are a cause of Wolfram syndrome 2. [provided by RefSeq, Mar 2011]
生物功能	Regulator of autophagy that contributes to antagonize BECN1-mediated cellular autophagy at the endoplasmic reticulum. Participates in the interaction of BCL2 with BECN1 and is required for BCL2-mediated depression of endoplasmic reticulum Ca(2+) stores during autophagy. Contributes to BIK-initiated autophagy, while it is not involved in BIK-dependent activation of caspases. Involved in life span control, probably via its function as regulator of autophagy. [UniProt]
预测分子量	15 kDa

检测图片 (1) Click the Picture to Zoom In