ARG57084
anti-CINP antibody [1G10]
anti-CINP antibody [1G10] for Western blot and Human
概述
| 产品描述 | Mouse Monoclonal antibody [1G10] recognizes CINP |
|---|---|
| 反应物种 | Hu |
| 应用 | WB |
| 宿主 | Mouse |
| 克隆 | Monoclonal |
| 克隆号 | 1G10 |
| 同位型 | IgG1, kappa |
| 靶点名称 | CINP |
| 抗原物种 | Human |
| 抗原 | Recombinant fragment around aa. 1-212 of Human CINP. |
| 偶联标记 | Un-conjugated |
| 別名 | CDK2-interacting protein; Cyclin-dependent kinase 2-interacting protein |
应用说明
| 应用建议 |
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| 应用说明 | * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. |
属性
| 形式 | Liquid |
|---|---|
| 纯化 | Purification with Protein A. |
| 缓冲液 | PBS (pH 7.4), 0.02% Sodium azide and 10% Glycerol. |
| 抗菌剂 | 0.02% Sodium azide |
| 稳定剂 | 10% Glycerol |
| 浓度 | 1 mg/ml |
| 存放说明 | For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
| 注意事项 | For laboratory research only, not for drug, diagnostic or other use. |
生物信息
| 数据库连接 |
Swiss-port # Q9BW66 Human Cyclin-dependent kinase 2-interacting protein |
|---|---|
| 基因名称 | CINP |
| 全名 | cyclin-dependent kinase 2 interacting protein |
| 背景介绍 | The protein encoded by this gene is reported to be a component of the DNA replication complex as well as a genome-maintenance protein. It may interact with proteins important for replication initiation and has been shown to bind chromatin at the G1 phase of the cell cycle and dissociate from chromatin with replication initiation. It may also serve to regulate checkpoint signaling as part of the DNA damage response. [provided by RefSeq, Jul 2013] |
| 生物功能 | Interacts with the components of the replication complex and 2 kinases, CDK2 and CDC7, thereby providing a functional and physical link between CDK2 and CDC7 during firing of the origins of replication. Regulates ATR-mediated checkpoint signaling. [UniProt] |
| 预测分子量 | 24 kDa |
| 翻译后修饰 | Phosphorylated by CDC7 but not by CDK2. |
检测图片 (1) Click the Picture to Zoom In
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ARG57084 anti-CINP antibody [1G10] WB image
Western blot: 40 µg of 1) Jurkat cell lysate, 2) K562 cell lysate, 3) 293T cell lysate, 4) HepG2 cell lysate, 5) A549 cell lysate, 6) MCF7 cell lysate, 7) LnCap cell lysate, 8) HeLa cell lysate, 9) SK-OV-3 cell lysate stained with ARG57084 anti-CINP antibody [1G10] at 1:1000.
