ARG58437
anti-CHRNE antibody
anti-CHRNE antibody for Western blot and Mouse
概述
| 产品描述 | Goat Polyclonal antibody recognizes CHRNE |
|---|---|
| 反应物种 | Ms |
| 预测物种 | Hu, Rat, Cow |
| 应用 | WB |
| 宿主 | Goat |
| 克隆 | Polyclonal |
| 同位型 | IgG |
| 靶点名称 | CHRNE |
| 抗原物种 | Human |
| 抗原 | Synthetic peptide from the internal region of Human CHRNE (NP_000071.1). (C-DQEATGEEVSD) |
| 偶联标记 | Un-conjugated |
| 別名 | FCCMS; CMS1E; CMS1D; SCCMS; CMS2A; Acetylcholine receptor subunit epsilon; CMS4B; CMS4C; ACHRE; CMS4A |
应用说明
| 应用建议 |
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| 应用说明 | WB: Recommend incubate at RT for 1h. * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. |
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| 实际分子量 | ~ 55 kDa |
属性
| 形式 | Liquid |
|---|---|
| 纯化 | Affinity purified |
| 缓冲液 | Tris saline (pH 7.3), 0.02% Sodium azide and 0.5% BSA. |
| 抗菌剂 | 0.02% Sodium azide |
| 稳定剂 | 0.5% BSA |
| 浓度 | 0.5 mg/ml |
| 存放说明 | For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C or below. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
| 注意事项 | For laboratory research only, not for drug, diagnostic or other use. |
生物信息
| 数据库连接 |
Swiss-port # P20782 Mouse Acetylcholine receptor subunit epsilon |
|---|---|
| 基因名称 | CHRNE |
| 全名 | cholinergic receptor, nicotinic, epsilon (muscle) |
| 背景介绍 | Acetylcholine receptors at mature mammalian neuromuscular junctions are pentameric protein complexes composed of four subunits in the ratio of two alpha subunits to one beta, one epsilon, and one delta subunit. The acetylcholine receptor changes subunit composition shortly after birth when the epsilon subunit replaces the gamma subunit seen in embryonic receptors. Mutations in the epsilon subunit are associated with congenital myasthenic syndrome. [provided by RefSeq, Sep 2009] |
| 生物功能 | After binding acetylcholine, the AChR responds by an extensive change in conformation that affects all subunits and leads to opening of an ion-conducting channel across the plasma membrane. [UniProt] |
| 预测分子量 | 55 kDa |
检测图片 (1) Click the Picture to Zoom In
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ARG58437 anti-CHRNE antibody WB image
Western blot: 35 µg of Mouse fetal skeletal muscle lysate (in RIPA buffer) stained with ARG58437 anti-CHRNE antibody at 1 µg/ml dilution. Primary incubation was 1 hour. Detected by chemiluminescence.
