ARG55213
anti-CHRNA9 antibody
anti-CHRNA9 antibody for Flow cytometry,Western blot and Human
Neuroscience antibody
概述
| 产品描述 | Rabbit Polyclonal antibody recognizes CHRNA9 |
|---|---|
| 反应物种 | Hu |
| 应用 | FACS, WB |
| 宿主 | Rabbit |
| 克隆 | Polyclonal |
| 同位型 | IgG |
| 靶点名称 | CHRNA9 |
| 抗原物种 | Human |
| 抗原 | KLH-conjugated synthetic peptide corresponding to aa. 8-42 (N-terminus) of Human CHRNA9. |
| 偶联标记 | Un-conjugated |
| 別名 | Neuronal acetylcholine receptor subunit alpha-9; HSA243342; NACHRA9; Nicotinic acetylcholine receptor subunit alpha-9; NACHR alpha-9 |
应用说明
| 应用建议 |
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|---|---|---|---|---|---|---|---|
| 应用说明 | * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. | ||||||
| 阳性对照 | Daudi |
属性
| 形式 | Liquid |
|---|---|
| 纯化 | Purification with Protein A and immunogen peptide. |
| 缓冲液 | PBS and 0.09% (W/V) Sodium azide |
| 抗菌剂 | 0.09% (W/V) Sodium azide |
| 存放说明 | For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C or below. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
| 注意事项 | For laboratory research only, not for drug, diagnostic or other use. |
生物信息
| 数据库连接 |
Swiss-port # Q9UGM1 Human Neuronal acetylcholine receptor subunit alpha-9 |
|---|---|
| 基因名称 | CHRNA9 |
| 全名 | cholinergic receptor, nicotinic, alpha 9 (neuronal) |
| 背景介绍 | This gene is a member of the ligand-gated ionic channel family and nicotinic acetylcholine receptor gene superfamily. It encodes a plasma membrane protein that forms homo- or hetero-oligomeric divalent cation channels. This protein is involved in cochlea hair cell development and is also expressed in the outer hair cells (OHCs) of the adult cochlea. [provided by RefSeq, Feb 2012] |
| 生物功能 | Ionotropic receptor with a probable role in the modulation of auditory stimuli. Agonist binding induces a conformation change that leads to the opening of an ion-conducting channel across the plasma membrane (PubMed:11752216, PubMed:25282151). The channel is permeable to a range of divalent cations including calcium, the influx of which may activate a potassium current which hyperpolarizes the cell membrane (PubMed:11752216, PubMed:25282151). In the ear, this may lead to a reduction in basilar membrane motion, altering the activity of auditory nerve fibers and reducing the range of dynamic hearing. This may protect against acoustic trauma. May also regulate keratinocyte adhesion (PubMed:11021840). [UniProt] |
| 细胞定位 | Cell junction, synapse, postsynaptic cell membrane; Multi-pass membrane protein Cell membrane; Multi-pass membrane protein |
| 研究领域 | Neuroscience antibody |
| 预测分子量 | 55 kDa |
| 翻译后修饰 | N-glycosylated. |
检测图片 (2) Click the Picture to Zoom In
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ARG55213 anti-CHRNA9 antibody WB image
Western blot: 35 µg of Daudi cell lysate stained with ARG55213 anti-CHRNA9 antibody at 1:1000 dilution.
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ARG55213 anti-CHRNA9 antibody FACS image
Flow Cytometry: Jurkat cells stained with ARG55213 anti-CHRNA9 antibody (right histogram) at 1:25 dilution or without primary antibodies (left histogram), followed by incubation with Alexa Fluor® 488 labelled secondary antibody.
