ARG64681
anti-CHRNA4 antibody
anti-CHRNA4 antibody for Western blot and Human,Rat
Cancer antibody; Metabolism antibody; Neuroscience antibody
概述
| 产品描述 | Goat Polyclonal antibody recognizes CHRNA4 |
|---|---|
| 反应物种 | Hu, Rat |
| 预测物种 | Ms, Cow, Dog |
| 应用 | WB |
| 特异性 | This antibody is expected NOT to cross-react with the similar alpha 2 subunit. |
| 宿主 | Goat |
| 克隆 | Polyclonal |
| 同位型 | IgG |
| 靶点名称 | CHRNA4 |
| 抗原物种 | Human |
| 抗原 | C-HVETRAHAEERLLKK |
| 偶联标记 | Un-conjugated |
| 別名 | Neuronal acetylcholine receptor subunit alpha-4; NACRA4; NACHRA4; EBN; BFNC; EBN1; NACHR |
应用说明
| 应用建议 |
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|---|---|---|---|---|---|
| 应用说明 | WB: Recommend incubate at RT for 1h. * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. |
属性
| 形式 | Liquid |
|---|---|
| 纯化 | Purified from goat serum by antigen affinity chromatography. |
| 缓冲液 | Tris saline (pH 7.3), 0.02% Sodium azide and 0.5% BSA. |
| 抗菌剂 | 0.02% Sodium azide |
| 稳定剂 | 0.5% BSA |
| 浓度 | 0.5 mg/ml |
| 存放说明 | For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C or below. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
| 注意事项 | For laboratory research only, not for drug, diagnostic or other use. |
生物信息
| 数据库连接 |
Swiss-port # P09483 Rat Neuronal acetylcholine receptor subunit alpha-4 Swiss-port # P43681 Human Neuronal acetylcholine receptor subunit alpha-4 |
|---|---|
| 背景介绍 | This gene encodes a nicotinic acetylcholine receptor, which belongs to a superfamily of ligand-gated ion channels that play a role in fast signal transmission at synapses. These pentameric receptors can bind acetylcholine, which causes an extensive change in conformation that leads to the opening of an ion-conducting channel across the plasma membrane. This protein is an integral membrane receptor subunit that can interact with either nAChR beta-2 or nAChR beta-4 to form a functional receptor. Mutations in this gene cause nocturnal frontal lobe epilepsy type 1. Polymorphisms in this gene that provide protection against nicotine addiction have been described. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Feb 2012] |
| 研究领域 | Cancer antibody; Metabolism antibody; Neuroscience antibody |
| 预测分子量 | 70 kDa |
检测图片 (1) Click the Picture to Zoom In
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ARG64681 anti-CHRNA4 antibody WB image
Western Blot: Rat Brain lysate (35 µg protein in RIPA buffer) stained with ARG64681 anti-CHRNA4 (aa29-43) antibody at 0.3 µg/ml dilution.
