ARG45173
anti-CHRM1 / M1 mAChR antibody
anti-CHRM1 / M1 mAChR antibody for Flow cytometry,IHC-Formalin-fixed paraffin-embedded sections,Western blot and Human,Mouse,Rat
概述
| 产品描述 | Rabbit Polyclonal antibody recognizes CHRM1 / M1 mAChR |
|---|---|
| 反应物种 | Hu, Ms, Rat |
| 应用 | FACS, IHC-P, WB |
| 宿主 | Rabbit |
| 克隆 | Polyclonal |
| 同位型 | IgG |
| 靶点名称 | CHRM1 / M1 mAChR |
| 抗原物种 | Human |
| 抗原 | Synthetic peptide corresponding to C-terminal region of human CHRM1 / M1 mAChR. |
| 偶联标记 | Un-conjugated |
| 別名 | CHRM1; cholinergic receptor muscarinic 1; Muscarinic acetylcholine receptor M1; CHRM1 |
应用说明
| 应用建议 |
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| 应用说明 | * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. | ||||||||
| 实际分子量 | 55 kDa |
属性
| 形式 | Liquid |
|---|---|
| 纯化 | Affinity purification with immunogen. |
| 缓冲液 | 0.2% Na2HPO4, 0.9% NaCl, 0.05% Sodium azide and 4% Trehalose. |
| 抗菌剂 | 0.05% Sodium azide |
| 稳定剂 | 4% Trehalose |
| 浓度 | 0.5 mg/ml |
| 存放说明 | For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C or below. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
| 注意事项 | For laboratory research only, not for drug, diagnostic or other use. |
生物信息
| 数据库连接 | |
|---|---|
| 基因名称 | CHRM1 |
| 全名 | cholinergic receptor muscarinic 1 |
| 背景介绍 | The muscarinic cholinergic receptors belong to a larger family of G protein-coupled receptors. The functional diversity of these receptors is defined by the binding of acetylcholine and includes cellular responses such as adenylate cyclase inhibition, phosphoinositide degeneration, and potassium channel mediation. Muscarinic receptors influence many effects of acetylcholine in the central and peripheral nervous system. The muscarinic cholinergic receptor 1 is involved in mediation of vagally-induced bronchoconstriction and in the acid secretion of the gastrointestinal tract. The gene encoding this receptor is localized to 11q13. [provided by RefSeq, Jul 2008] |
| 生物功能 | The muscarinic acetylcholine receptor mediates various cellular responses, including inhibition of adenylate cyclase, breakdown of phosphoinositides and modulation of potassium channels through the action of G proteins. Primary transducing effect is Pi turnover. [UniProt] |
| 细胞定位 | Cell membrane; Multi-pass membrane protein. Cell junction, synapse, postsynaptic cell membrane; Multi-pass membrane protein. [UniProt] |
| 预测分子量 | 51 kDa |
| 翻译后修饰 | Disulfide bond; Glycoprotein; Phosphoprotein. [UniProt] |
检测图片 (4) Click the Picture to Zoom In
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ARG45173 anti-CHRM1 / M1 mAChR antibody WB image
Western blot: C6 stained with ARG45173 anti-CHRM1 / M1 mAChR antibody at 0.5 μg/ml dilution.
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ARG45173 anti-CHRM1 / M1 mAChR antibody FACS image
Flow Cytometry: Rat brain stained with ARG45173 anti-CHRM1 / M1 mAChR antibody at 1 µg/10^6 cells dilution.
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ARG45173 anti-CHRM1 / M1 mAChR antibody IHC-P image
Immunohistochemistry: Mouse brain stained with ARG45173 anti-CHRM1 / M1 mAChR antibody at 1 μg/ml dilution.
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ARG45173 anti-CHRM1 / M1 mAChR antibody WB image
Western blot: Neuro-2A stained with ARG45173 anti-CHRM1 / M1 mAChR antibody at 0.5 μg/ml dilution.
