anti-CHOP / GADD153 antibody

anti-CHOP / GADD153 antibody for Immunohistochemistry,Immunoprecipitation,Western blot and Human,Mouse,Rat

Developmental Biology antibody; Gene Regulation antibody; Metabolism antibody
publication_link 参考文献1



Rabbit Polyclonal antibody recognizes CHOP / GADD153

反应物种 Hu, Ms, Rat
应用 IHC, IP, WB
特异性 The antibody recognizes 25 kDa GADD153 of human, mouse, and rat origins.
宿主 Rabbit
克隆 Polyclonal
同位型 IgG
靶点名称 CHOP / GADD153
抗原物种 Human
抗原 Synthetic peptide surrounding amino acid 124 of human GADD153
偶联标记 Un-conjugated
別名 DNA damage-inducible transcript 3 protein; CHOP10; Growth arrest and DNA damage-inducible protein GADD153; GADD153; CCAAT/enhancer-binding protein homologous protein; C/EBP-homologous protein; CHOP; CHOP-10; C/EBP zeta; CEBPZ; DDIT-3; C/EBP-homologous protein 10


应用 推荐稀释比
IHC10-20 µg/ml
IP10-20 µg/ml
WB0.5-4 µg/ml
应用说明 * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist.


形式 Liquid
纯化 Affinity Purified Antibody
缓冲液 PBS, 30% Glycerol, 0.5% BSA and 0.01% Thimerosal
抗菌剂 0.01% Thimerosal
稳定剂 30% Glycerol, 0.5% BSA
浓度 0.2 mg/ml
存放说明 For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use.
注意事项 For laboratory research only, not for drug, diagnostic or other use.



GeneID: 13198 Mouse DDIT3

GeneID: 1649 Human DDIT3

Swiss-port # P35638 Human DNA damage-inducible transcript 3 protein

Swiss-port # P35639 Mouse DNA damage-inducible transcript 3 protein

背景介绍 GADD153 has been described as a growth arrest and DNA damage-inducible gene that encodes a C/EBP-related nuclear protein. Expression of GADD153 is induced by a variety of cellular stresses, including nutrient deprivation and metabolic perturbations. GADD153 functions to block cells in G1 to S phase in cell cycle progression and acts by dimerizing with other C/EBP proteins to direct GADD153 dimers away from “classical” C/EBP binding sites. Thus GADD153 acts as a negative modulator of C/EBP-like proteins in certain terminally differentiated cells.
研究领域 Developmental Biology antibody; Gene Regulation antibody; Metabolism antibody
预测分子量 19 kDa
翻译后修饰 Ubiquitinated, leading to its degradation by the proteasome.
Phosphorylation at serine residues by MAPK14 enhances its transcriptional activation activity while phosphorylation at serine residues by CK2 inhibits its transcriptional activation activity.


Mangiferin alleviates endoplasmic reticulum stress in acute liver injury by regulating the miR-20a/miR-101a-Nrf2 axis.

WB / Mouse

Shaoxun Li et al.
J Biochem.,  (2020)