概述

产品描述	Rabbit Polyclonal antibody recognizes CHD4
反应物种	Hu
应用	FACS, ICC/IF, WB
宿主	Rabbit
克隆	Polyclonal
同位型	IgG
靶点名称	CHD4
抗原物种	Human
抗原	Synthetic peptide of Human CHD4.
偶联标记	Un-conjugated
別名	Chromodomain-helicase-DNA-binding protein 4; Mi-2b; EC 3.6.4.12; Mi-2 autoantigen 218 kDa protein; CHD-4; Mi2-beta; ATP-dependent helicase CHD4; Mi2-BETA

应用说明

应用建议	应用 推荐稀释比 FACS 1:50 ICC/IF 1:50 - 1:200 WB 1:1000 - 1:5000
应用说明	* The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist.
阳性对照	293T

属性

形式	Liquid
纯化	Affinity purified.
缓冲液	PBS (pH 7.4), 150 mM NaCl, 0.02% Sodium azide and 50% Glycerol.
抗菌剂	0.02% Sodium azide
稳定剂	50% Glycerol
存放说明	For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use.
注意事项	For laboratory research only, not for drug, diagnostic or other use.

生物信息

数据库连接	GeneID: 1108 Human CHD4 Swiss-port # Q14839 Human Chromodomain-helicase-DNA-binding protein 4
基因名称	CHD4
全名	chromodomain helicase DNA binding protein 4
背景介绍	The product of this gene belongs to the SNF2/RAD54 helicase family. It represents the main component of the nucleosome remodeling and deacetylase complex and plays an important role in epigenetic transcriptional repression. Patients with dermatomyositis develop antibodies against this protein. Somatic mutations in this gene are associated with serous endometrial tumors. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Jul 2014]
生物功能	Component of the histone deacetylase NuRD complex which participates in the remodeling of chromatin by deacetylating histones. [UniProt]
细胞定位	Nucleus. Cytoplasm, cytoskeleton, microtubule organizing center, centrosome. Note=Associates with centrosomes in interphase. [UniProt]
预测分子量	218 kDa

检测图片 (1) Click the Picture to Zoom In