ARG40244
anti-CHAC1 antibody
anti-CHAC1 antibody for Western blot and Human,Mouse,Rat
概述
| 产品描述 | Rabbit Polyclonal antibody recognizes CHAC1 |
|---|---|
| 反应物种 | Hu, Ms, Rat |
| 应用 | WB |
| 宿主 | Rabbit |
| 克隆 | Polyclonal |
| 同位型 | IgG |
| 靶点名称 | CHAC1 |
| 抗原物种 | Human |
| 抗原 | KLH-conjugated synthetic peptide within the N-terminal region of Human CHAC1. |
| 偶联标记 | Un-conjugated |
| 別名 | Botch; Gamma-GCG 1; Glutathione-specific gamma-glutamylcyclotransferase 1; Cation transport regulator-like protein 1; EC 2.3.2.-; Blocks Notch protein |
应用说明
| 应用建议 |
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| 应用说明 | * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. | ||||
| 实际分子量 | ~ 24 kDa |
属性
| 形式 | Liquid |
|---|---|
| 纯化 | Affinity purification with immunogen. |
| 缓冲液 | 0.42% Potassium phosphate (pH 7.3), 0.87% NaCl, 0.01% Sodium azide and 30% Glycerol. |
| 抗菌剂 | 0.01% Sodium azide |
| 稳定剂 | 30% Glycerol |
| 存放说明 | For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
| 注意事项 | For laboratory research only, not for drug, diagnostic or other use. |
生物信息
| 数据库连接 | |
|---|---|
| 基因名称 | CHAC1 |
| 全名 | ChaC glutathione-specific gamma-glutamylcyclotransferase 1 |
| 生物功能 | Catalyzes the cleavage glutathione into 5-oxoproline and a Cys-Gly dipeptide. Acts specifically on glutathione, but not on other gamma-glutamyl peptides. Glutathione depletion is an important factor for apoptosis initiation and execution. Acts as a pro-apoptotic component of the unfolded protein response pathway by mediating the pro-apoptotic effects of the ATF4-ATF3-DDIT3/CHOP cascade. Negative regulator of Notch signaling pathway involved in embryonic neurogenesis: acts by inhibiting Notch cleavage by furin, maintaining Notch in an immature inactive form, thereby promoting neurogenesis in embryos. [UniProt] |
| 细胞定位 | Cytoplasm, cytosol. Golgi apparatus, trans-Golgi network. [UniProt] |
| 预测分子量 | 24 kDa |
检测图片 (1) Click the Picture to Zoom In
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ARG40244 anti-CHAC1 antibody WB image
Western blot: U2OS, HeLa, Raw264.7 and PC12 whole cell lysates stained with ARG40244 anti-CHAC1 antibody.
