ARG55300
anti-CES1 antibody
anti-CES1 antibody for Western blot and Human,Mouse
Cell Biology and Cellular Response antibody; Metabolism antibody; Signaling Transduction antibody
概述
| 产品描述 | Rabbit Polyclonal antibody recognizes CES1 |
|---|---|
| 反应物种 | Hu, Ms |
| 应用 | WB |
| 宿主 | Rabbit |
| 克隆 | Polyclonal |
| 同位型 | IgG |
| 靶点名称 | CES1 |
| 抗原物种 | Human |
| 抗原 | Recombinant protein of Human CES1 |
| 偶联标记 | Un-conjugated |
| 別名 | SES1; Cocaine carboxylesterase; REH; ACAT; Serine esterase 1; HMSE; Retinyl ester hydrolase; Methylumbelliferyl-acetate deacetylase 1; hCE-1; EC 3.1.1.56; CE-1; CEH; HMSE1; TGH; PCE-1; Acyl-coenzyme A:cholesterol acyltransferase; EC 3.1.1.1; Liver carboxylesterase 1; Brain carboxylesterase hBr1; Triacylglycerol hydrolase; CES2; Egasyn; Carboxylesterase 1; Monocyte/macrophage serine esterase |
应用说明
| 应用建议 |
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|---|---|---|---|---|---|
| 应用说明 | * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. | ||||
| 阳性对照 | A549 and Mouse liver |
属性
| 形式 | Liquid |
|---|---|
| 纯化 | Affinity purification with immunogen. |
| 缓冲液 | PBS (pH 7.3), 0.02% Sodium azide and 50% Glycerol |
| 抗菌剂 | 0.02% Sodium azide |
| 稳定剂 | 50% Glycerol |
| 存放说明 | For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
| 注意事项 | For laboratory research only, not for drug, diagnostic or other use. |
生物信息
| 数据库连接 | |
|---|---|
| 基因名称 | CES1 |
| 全名 | carboxylesterase 1 |
| 背景介绍 | This gene encodes a member of the carboxylesterase large family. The family members are responsible for the hydrolysis or transesterification of various xenobiotics, such as cocaine and heroin, and endogenous substrates with ester, thioester, or amide bonds. They may participate in fatty acyl and cholesterol ester metabolism, and may play a role in the blood-brain barrier system. This enzyme is the major liver enzyme and functions in liver drug clearance. Mutations of this gene cause carboxylesterase 1 deficiency. Three transcript variants encoding three different isoforms have been found for this gene. [provided by RefSeq, Jun 2010] |
| 生物功能 | Involved in the detoxification of xenobiotics and in the activation of ester and amide prodrugs. Hydrolyzes aromatic and aliphatic esters, but has no catalytic activity toward amides or a fatty acyl-CoA ester. Hydrolyzes the methyl ester group of cocaine to form benzoylecgonine. Catalyzes the transesterification of cocaine to form cocaethylene. Displays fatty acid ethyl ester synthase activity, catalyzing the ethyl esterification of oleic acid to ethyloleate. [UniProt] |
| 研究领域 | Cell Biology and Cellular Response antibody; Metabolism antibody; Signaling Transduction antibody |
| 预测分子量 | 63 kDa |
| 翻译后修饰 | Contains sialic acid. Cleavage of the signal sequence can occur at 2 positions, either between Trp-17 and Gly-18 or between Gly-18 and His-19. |
检测图片 (1) Click the Picture to Zoom In
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ARG55300 anti-CES1 antibody WB image
Western blot: A549 and Mouse liver lysates stained with ARG55300 anti-CES1 antibody.
