概述

产品描述	Rabbit Polyclonal antibody recognizes CERK
反应物种	Hu, Ms
应用	WB
宿主	Rabbit
克隆	Polyclonal
同位型	IgG
靶点名称	CERK
抗原物种	Human
抗原	KLH-conjugated synthetic peptide corresponding to aa. 487-516 (C-terminus) of Human CERK.
偶联标记	Un-conjugated
別名	dA59H18.3; dA59H18.2; hCERK; Ceramide kinase; Lipid kinase 4; LK4; Acylsphingosine kinase; EC 2.7.1.138

应用说明

应用建议	应用 推荐稀释比 WB 1:1000
应用说明	* The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist.
阳性对照	Mouse heart

属性

形式	Liquid
纯化	Purification with Protein G.
缓冲液	PBS and 0.09% (W/V) Sodium azide
抗菌剂	0.09% (W/V) Sodium azide
存放说明	For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C or below. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use.
注意事项	For laboratory research only, not for drug, diagnostic or other use.

生物信息

数据库连接	GeneID: 223753 Mouse CERK GeneID: 64781 Human CERK Swiss-port # Q8K4Q7 Mouse Ceramide kinase Swiss-port # Q8TCT0 Human Ceramide kinase
基因名称	CERK
全名	ceramide kinase
背景介绍	CERK converts ceramide to ceramide 1-phosphate (C1P), a sphingolipid metabolite. Both CERK and C1P have been implicated in various cellular processes, including proliferation, apoptosis, phagocytosis, and inflammation (Kim et al., 2006 [PubMed 16488390]).[supplied by OMIM, Mar 2008]
生物功能	Catalyzes specifically the phosphorylation of ceramide to form ceramide 1-phosphate. Acts efficiently on natural and analog ceramides (C6, C8, C16 ceramides, and C8-dihydroceramide), to a lesser extent on C2-ceramide and C6-dihydroceramide, but not on other lipids, such as various sphingosines. Binds phosphoinositides. [UniProt]
细胞定位	Cytoplasm. Membrane; Peripheral membrane protein
研究领域	Cell Biology and Cellular Response antibody; Cell Death antibody
预测分子量	60 kDa

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