ARG66605
anti-CEP135 antibody
anti-CEP135 antibody for ICC/IF,IHC-Formalin-fixed paraffin-embedded sections,Western blot and Human,Mouse
概述
| 产品描述 | Rabbit Polyclonal antibody recognizes CEP135 |
|---|---|
| 反应物种 | Hu, Ms |
| 应用 | ICC/IF, IHC-P, WB |
| 宿主 | Rabbit |
| 克隆 | Polyclonal |
| 同位型 | IgG |
| 靶点名称 | CEP135 |
| 抗原物种 | Human |
| 抗原 | Synthetic peptide within aa. 1050-1130 of Human CEP135. |
| 偶联标记 | Un-conjugated |
| 別名 | Centrosomal protein of 135 kDa; KIAA0635; MCPH8; CEP4; Cep135; Centrosomal protein 4 |
应用说明
| 应用建议 |
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| 应用说明 | IHC-P: Antigen Retrieval: High-pressure and temperature Tris-EDTA buffer (pH 8.0). * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. |
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| 实际分子量 | ~ 130 kDa |
属性
| 形式 | Liquid |
|---|---|
| 纯化 | Affinity purification with immunogen. |
| 缓冲液 | PBS, 0.02% Sodium azide, 50% Glycerol and 0.5% BSA. |
| 抗菌剂 | 0.02% Sodium azide |
| 稳定剂 | 50% Glycerol and 0.5% BSA |
| 浓度 | 1 mg/ml |
| 存放说明 | For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
| 注意事项 | For laboratory research only, not for drug, diagnostic or other use. |
生物信息
| 数据库连接 | |
|---|---|
| 基因名称 | CEP135 |
| 全名 | centrosomal protein 135kDa |
| 背景介绍 | This gene encodes a centrosomal protein, which acts as a scaffolding protein during early centriole biogenesis, and is also required for centriole-centriole cohesion during interphase. Mutations in this gene are associated with autosomal recessive primary microcephaly-8. [provided by RefSeq, Jun 2012] |
| 生物功能 | Centrosomal protein involved in centriole biogenesis. Acts as a scaffolding protein during early centriole biogenesis. Also required for centriole-centriole cohesion during interphase by acting as a platform protein for CEP250 at the centriole. [UniProt] |
| 细胞定位 | Cytoplasm, cytoskeleton, microtubule organizing center, centrosome, centriole. Note=During centriole biogenesis, it is concentrated within the proximal lumen of both parental centrioles and procentrioles. [UniProt] |
| 预测分子量 | 133 kDa |
检测图片 (2) Click the Picture to Zoom In
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ARG66605 anti-CEP135 antibody IHC-P image
Immunohistochemistry: Paraffin-embedded Human brain tissue stained with ARG66605 anti-CEP135 antibody at 1:100 dilution (4°C, overnight). Antigen Retrieval: High-pressure and temperature Tris-EDTA buffer (pH 8.0). Negative control (right) was pre-absorbed by immunogen peptide.
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ARG66605 anti-CEP135 antibody WB image
Western blot: Mouse lung, Mouse heart and 293T cell lysates stained with ARG66605 anti-CEP135 antibody at 1:1000 dilution.
