ARG46377
anti-CENTG1 / PIKE antibody
anti-CENTG1 / PIKE antibody for Western blot,IHC-Formalin-fixed paraffin-embedded sections and Human,Mouse
概述
| 产品描述 | Rabbit Polyclonal antibody recognizes CENTG1 / PIKE |
|---|---|
| 反应物种 | Hu, Ms |
| 应用 | IHC-P, WB |
| 宿主 | Rabbit |
| 克隆 | Polyclonal |
| 同位型 | IgG |
| 靶点名称 | CENTG1 / PIKE |
| 抗原物种 | Human |
| 抗原 | A 15 amino acid synthetic peptide within the last 50 amino acids of human CENTG1 / PIKE. |
| 偶联标记 | Un-conjugated |
| 別名 | AGAP2; PIKE; GGAP2; AGAP-2; Cnt-g1; Arf-GAP with GTPase, ANK repeat and PH domain-containing protein 2; Phosphatidylinositol 3-kinase enhancer; Centaurin-gamma-1; GTP-binding and GTPase-activating protein 2; CENTG1 |
应用说明
| 应用建议 |
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| 应用说明 | * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. |
属性
| 纯化 | Ion exchange chromatography purified |
|---|---|
| 缓冲液 | PBS and 0.02% Sodium azide. |
| 抗菌剂 | 0.02% Sodium azide |
| 浓度 | 1 mg/ml |
| 存放说明 | For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
| 注意事项 | For laboratory research only, not for drug, diagnostic or other use. |
生物信息
| 数据库连接 |
Swiss-port # Q3UHD9 Mouse Arf-GAP with GTPase, ANK repeat and PH domain-containing protein 2 Swiss-port # Q99490 Human Arf-GAP with GTPase, ANK repeat and PH domain-containing protein 2 |
|---|---|
| 基因名称 | AGAP2 |
| 全名 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 2 |
| 背景介绍 | The protein encoded by this gene belongs to the centaurin gamma-like family. It mediates anti-apoptotic effects of nerve growth factor by activating nuclear phosphoinositide 3-kinase. It is overexpressed in cancer cells, and promotes cancer cell invasion. Alternatively spliced transcript variants encoding different isoforms have been described for this gene. [provided by RefSeq, Aug 2011] |
| 预测分子量 | 125 kDa |
| 翻译后修饰 | Isoform PIKE-A is phosphorylated at Tyr-682 and Tyr-774 by FYN, preventing its apoptotic cleavage. |
