ARG63565
anti-CENTB1 / ACAP1 antibody
anti-CENTB1 / ACAP1 antibody for Western blot and Human
Signaling Transduction antibody
概述
| 产品描述 | Goat Polyclonal antibody recognizes CENTB1 / ACAP1 |
|---|---|
| 反应物种 | Hu |
| 预测物种 | Ms, Rat, Cow, Dog |
| 应用 | WB |
| 宿主 | Goat |
| 克隆 | Polyclonal |
| 同位型 | IgG |
| 靶点名称 | CENTB1 / ACAP1 |
| 抗原物种 | Human |
| 抗原 | C-EKLSRRSHDLHTL |
| 偶联标记 | Un-conjugated |
| 別名 | Arf-GAP with coiled-coil, ANK repeat and PH domain-containing protein 1; Centaurin-beta-1; CENTB1; Cnt-b1 |
应用说明
| 应用建议 |
|
||||
|---|---|---|---|---|---|
| 应用说明 | WB: Recommend incubate at RT for 1h. * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. |
属性
| 形式 | Liquid |
|---|---|
| 纯化 | Purified from goat serum by antigen affinity chromatography. |
| 缓冲液 | Tris saline (pH 7.3), 0.02% Sodium azide and 0.5% BSA. |
| 抗菌剂 | 0.02% Sodium azide |
| 稳定剂 | 0.5% BSA |
| 浓度 | 0.5 mg/ml |
| 存放说明 | For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C or below. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
| 注意事项 | For laboratory research only, not for drug, diagnostic or other use. |
生物信息
| 数据库连接 |
Swiss-port # Q15027 Human Arf-GAP with coiled-coil, ANK repeat and PH domain-containing protein 1 |
|---|---|
| 基因名称 | ACAP1 |
| 全名 | ArfGAP with coiled-coil, ankyrin repeat and PH domains 1 |
| 生物功能 | GTPase-activating protein (GAP) for ADP ribosylation factor 6 (ARF6) required for clathrin-dependent export of proteins from recycling endosomes to trans-Golgi network and cell surface. Required for regulated export of ITGB1 from recycling endosomes to the cell surface and ITGB1-dependent cell migration. [UniProt] |
| 研究领域 | Signaling Transduction antibody |
| 预测分子量 | 82 kDa |
| 翻译后修饰 | Phosphorylation at Ser-554 by PKB is required for interaction with ITGB1, export of ITGB1 from recycling endosomes to the cell surface and ITGB1-dependent cell migration. |
检测图片 (1) Click the Picture to Zoom In
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ARG63565 anti-CENTB1 / ACAP1 antibody WB image
Western Blot: Jurkat lysate (RIPA buffer, 35µg total protein per lane) stained with ARG63565 anti-CENTB1 / ACAP1 antibody diluted in 0.5µg/ml.
