ARG41324
anti-CENPK antibody
anti-CENPK antibody for Western blot and Human
概述
| 产品描述 | Rabbit Polyclonal antibody recognizes CENPK |
|---|---|
| 反应物种 | Hu |
| 应用 | WB |
| 宿主 | Rabbit |
| 克隆 | Polyclonal |
| 同位型 | IgG |
| 靶点名称 | CENPK |
| 抗原物种 | Human |
| 抗原 | Recombinant fusion protein corresponding to aa. 1-269 of Human CENPK (NP_071428.2). |
| 偶联标记 | Un-conjugated |
| 別名 | FKSG14; p33; Centromere protein K; Interphase centromere complex protein 37; Protein AF-5alpha; CENP-K; P33; Solt; AF5alpha |
应用说明
| 应用建议 |
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| 应用说明 | * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. | ||||
| 阳性对照 | SKOV3 | ||||
| 实际分子量 | 37 kDa |
属性
| 形式 | Liquid |
|---|---|
| 纯化 | Affinity purified. |
| 缓冲液 | PBS (pH 7.3), 0.02% Sodium azide and 50% Glycerol. |
| 抗菌剂 | 0.02% Sodium azide |
| 稳定剂 | 50% Glycerol |
| 存放说明 | For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
| 注意事项 | For laboratory research only, not for drug, diagnostic or other use. |
生物信息
| 数据库连接 | |
|---|---|
| 基因名称 | CENPK |
| 全名 | centromere protein K |
| 背景介绍 | CENPK is a subunit of a CENPH (MIM 605607)-CENPI (MIM 300065)-associated centromeric complex that targets CENPA (MIM 117139) to centromeres and is required for proper kinetochore function and mitotic progression (Okada et al., 2006 [PubMed 16622420]).[supplied by OMIM, Mar 2008] |
| 生物功能 | Component of the CENPA-CAD (nucleosome distal) complex, a complex recruited to centromeres which is involved in assembly of kinetochore proteins, mitotic progression and chromosome segregation. May be involved in incorporation of newly synthesized CENPA into centromeres via its interaction with the CENPA-NAC complex. Acts in coordination with CASC5/KNL1 to recruit the NDC80 complex to the outer kinetochore. [UniProt] |
| 细胞定位 | Nucleus. Chromosome, centromere. Chromosome, centromere, kinetochore. Note=Localizes exclusively in the centromeres. The CENPA-CAD complex is probably recruited on centromeres by the CENPA-NAC complex. [UniProt] |
| 预测分子量 | 32 kDa |
检测图片 (1) Click the Picture to Zoom In
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ARG41324 anti-CENPK antibody WB image
Western blot: 25 µg of SKOV3 cell lysate stained with ARG41324 anti-CENPK antibody at 1:1000 dilution.
