ARG56185
anti-CELA3B / Elastase 3B antibody [CELA3B/1218]
anti-CELA3B / Elastase 3B antibody [CELA3B/1218] for ELISA,Western blot and Human
概述
| 产品描述 | Mouse Monoclonal antibody [CELA3B/1218] recognizes CELA3B / Elastase 3B |
|---|---|
| 反应物种 | Hu |
| 不反应物种 | Rat |
| 应用 | ELISA, WB |
| 宿主 | Mouse |
| 克隆 | Monoclonal |
| 克隆号 | CELA3B/1218 |
| 同位型 | IgG, kappa |
| 靶点名称 | CELA3B / Elastase 3B |
| 抗原物种 | Human |
| 抗原 | A partial recombinant CELA3B protein (aa. 82-238). |
| 偶联标记 | Un-conjugated |
| 別名 | ELA3B; CBPP; EC 3.4.21.70; Elastase-3B; Chymotrypsin-like elastase family member 3B; Elastase IIIB; EL-1; Protease E; E1 |
应用说明
| 应用建议 |
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| 应用说明 | * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. |
属性
| 形式 | Liquid |
|---|---|
| 纯化 | Purification with Protein G. |
| 缓冲液 | PBS (pH 7.4), 0.05% Sodium azide and 0.1 mg/ml BSA. |
| 抗菌剂 | 0.05% Sodium azide |
| 稳定剂 | 0.1 mg/ml BSA |
| 浓度 | 0.2 mg/ml |
| 存放说明 | For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C or below. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
| 注意事项 | For laboratory research only, not for drug, diagnostic or other use. |
生物信息
| 数据库连接 |
Swiss-port # P08861 Human Chymotrypsin-like elastase family member 3B |
|---|---|
| 基因名称 | CELA3B |
| 全名 | chymotrypsin-like elastase family, member 3B |
| 背景介绍 | Elastases form a subfamily of serine proteases that hydrolyze many proteins in addition to elastin. Humans have six elastase genes which encode the structurally similar proteins elastase 1, 2, 2A, 2B, 3A, and 3B. Unlike other elastases, elastase 3B has little elastolytic activity. Like most of the human elastases, elastase 3B is secreted from the pancreas as a zymogen and, like other serine proteases such as trypsin, chymotrypsin and kallikrein, it has a digestive function in the intestine. Elastase 3B preferentially cleaves proteins after alanine residues. Elastase 3B may also function in the intestinal transport and metabolism of cholesterol. Both elastase 3A and elastase 3B have been referred to as protease E and as elastase 1, and excretion of this protein in fecal material is frequently used as a measure of pancreatic function in clinical assays. [provided by RefSeq, May 2009] |
| 生物功能 | Efficient protease with alanine specificity but only little elastolytic activity. [UniProt] |
| 细胞定位 | Cytoplasmic |
| 预测分子量 | 29 kDa |
检测图片 (1) Click the Picture to Zoom In
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ARG56185 anti-CELA3B / Elastase 3B antibody [CELA3B/1218] WB image
Western blot: 1) partial recombinant protein, 2) Panc-28, and 3) PANC1 cell lysates stained with ARG56185 anti-CELA3B / Elastase 3B antibody [CELA3B/1218].
