ARG40022
anti-CDK5RAP3 antibody
anti-CDK5RAP3 antibody for Western blot and Human
概述
| 产品描述 | Rabbit Polyclonal antibody recognizes CDK5RAP3 |
|---|---|
| 反应物种 | Hu |
| 应用 | WB |
| 宿主 | Rabbit |
| 克隆 | Polyclonal |
| 同位型 | IgG |
| 靶点名称 | CDK5RAP3 |
| 抗原物种 | Human |
| 抗原 | Recombinant fusion protein corresponding to aa. 1-300 of Human CDK5RAP3 (NP_788276.1). |
| 偶联标记 | Un-conjugated |
| 別名 | IC53; PP1553; C53; LZAP; Protein HSF-27; OK/SW-cl.114; CDK5 regulatory subunit-associated protein 3; MST016; LXXLL/leucine-zipper-containing ARF-binding protein; CDK5 activator-binding protein C53; HSF-27 |
应用说明
| 应用建议 |
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| 应用说明 | * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. | ||||
| 阳性对照 | U-87 MG | ||||
| 实际分子量 | 65 kDa |
属性
| 形式 | Liquid |
|---|---|
| 纯化 | Affinity purified. |
| 缓冲液 | PBS (pH 7.3), 0.02% Sodium azide and 50% Glycerol. |
| 抗菌剂 | 0.02% Sodium azide |
| 稳定剂 | 50% Glycerol |
| 存放说明 | For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
| 注意事项 | For laboratory research only, not for drug, diagnostic or other use. |
生物信息
| 数据库连接 |
Swiss-port # Q96JB5 Human CDK5 regulatory subunit-associated protein 3 |
|---|---|
| 基因名称 | CDK5RAP3 |
| 全名 | CDK5 regulatory subunit associated protein 3 |
| 背景介绍 | This gene encodes a protein that has been reported to function in signaling pathways governing transcriptional regulation and cell cycle progression. It may play a role in tumorigenesis and metastasis. A pseudogene of this gene is located on the long arm of chromosome 20. Alternative splicing results in multiple transcript variants that encode different isoforms. [provided by RefSeq, May 2013] |
| 生物功能 | Potential regulator of CDK5 activity. May be involved in cell proliferation. Regulates CDK5 activity via its interaction with CDK5R1 (By similarity). [UniProt] |
| 细胞定位 | Nucleus. Cytoplasm. Cytoplasm, cytoskeleton, microtubule organizing center, centrosome. Note=Colocalizes and associates with microtubules. [UniProt] |
| 预测分子量 | 57 kDa |
| 翻译后修饰 | May be phosphorylated by CDK5. Ubiquitinated. Probably triggers proteasomal degradation and is negatively regulated by UFL1. May be ufmylated. Cleaved by caspases early during apoptosis, the resulting peptides may play a role in rupture of the nuclear envelope. [UniProt] |
检测图片 (1) Click the Picture to Zoom In
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ARG40022 anti-CDK5RAP3 antibody WB image
Western blot: 25 µg of U-87 MG cell lysate stained with ARG40022 anti-CDK5RAP3 antibody at 1:1000 dilution.
