概述

产品描述	Rabbit Polyclonal antibody recognizes CDCA7
反应物种	Hu, Ms, Rat
应用	WB
宿主	Rabbit
克隆	Polyclonal
同位型	IgG
靶点名称	CDCA7
抗原物种	Human
抗原	Synthetic peptide around aa. 110-190 of Human CDCA7.
偶联标记	Un-conjugated
別名	JPO1; Cell division cycle-associated protein 7; Protein JPO1

应用说明

应用建议	应用 推荐稀释比 WB 1:500 - 1:2000
应用说明	* The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist.

属性

形式	Liquid
纯化	Affinity purification with immunogen.
缓冲液	PBS, 0.02% Sodium azide, 50% Glycerol and 0.5% BSA.
抗菌剂	0.02% Sodium azide
稳定剂	50% Glycerol and 0.5% BSA
浓度	1 mg/ml
存放说明	For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use.
注意事项	For laboratory research only, not for drug, diagnostic or other use.

生物信息

数据库连接	GeneID: 311742 Rat CDCA7 GeneID: 66953 Mouse CDCA7 GeneID: 83879 Human CDCA7 Swiss-port # Q4KM91 Rat Cell division cycle-associated protein 7 Swiss-port # Q9BWT1 Human Cell division cycle-associated protein 7 Swiss-port # Q9D0M2 Mouse Cell division cycle-associated protein 7 More
基因名称	CDCA7
全名	cell division cycle associated 7
背景介绍	This gene was identified as a c-Myc responsive gene, and behaves as a direct c-Myc target gene. Overexpression of this gene is found to enhance the transformation of lymphoblastoid cells, and it complements a transformation-defective Myc Box II mutant, suggesting its involvement in c-Myc-mediated cell transformation. Two alternatively spliced transcript variants encoding distinct isoforms have been reported. [provided by RefSeq, Jul 2008]
生物功能	Participates in MYC-mediated cell transformation and apoptosis; induces anchorage-independent growth and clonogenicity in lymphoblastoid cells. Insufficient to induce tumorigenicity when overexpressed but contributes to MYC-mediated tumorigenesis. May play a role as transcriptional regulator. [UniProt]
预测分子量	43 kDa
翻译后修饰	Phosphorylation at Thr-163 promotes interaction with YWHAE and YWHAZ, dissociation from MYC and sequestration in the cytoplasm. In vitro, phosphorylated at Thr-163 by AKT.

检测图片 (1) Click the Picture to Zoom In