ARG57313

anti-CDC45 antibody

anti-CDC45 antibody for Western blot and Human,Mouse,Rat

概述

产品描述 Rabbit Polyclonal antibody recognizes CDC45
反应物种 Hu, Ms, Rat
应用 WB
宿主 Rabbit
克隆 Polyclonal
同位型 IgG
靶点名称 CDC45
抗原物种 Human
抗原 Recombinant Protein of Human CDC45.
偶联标记 Un-conjugated
別名 Cell division control protein 45 homolog; CDC45L2; CDC45L; PORC-PI-1

应用说明

应用建议
应用 推荐稀释比
WB1:500 - 1:2000
应用说明 * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist.
阳性对照 HT-29

属性

形式 Liquid
纯化 Affinity purification with immunogen.
缓冲液 PBS (pH 7.3), 0.02% Sodium azide and 50% Glycerol.
抗菌剂 0.02% Sodium azide
稳定剂 50% Glycerol
存放说明 For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use.
注意事项 For laboratory research only, not for drug, diagnostic or other use.

生物信息

数据库连接

GeneID: 12544 Mouse CDC45

GeneID: 8318 Human CDC45

Swiss-port # O75419 Human Cell division control protein 45 homolog

Swiss-port # Q9Z1X9 Mouse Cell division control protein 45 homolog

基因名称 CDC45
全名 cell division cycle 45
背景介绍 The protein encoded by this gene was identified by its strong similarity with Saccharomyces cerevisiae Cdc45, an essential protein required to the initiation of DNA replication. Cdc45 is a member of the highly conserved multiprotein complex including Cdc6/Cdc18, the minichromosome maintenance proteins (MCMs) and DNA polymerase, which is important for early steps of DNA replication in eukaryotes. This protein has been shown to interact with MCM7 and DNA polymerase alpha. Studies of the similar gene in Xenopus suggested that this protein play a pivotal role in the loading of DNA polymerase alpha onto chromatin. Alternate splicing results in multiple transcript variants. [provided by RefSeq, Jul 2013]
生物功能 Required for initiation of chromosomal DNA replication. [UniProt]
预测分子量 66 kDa

检测图片 (1) Click the Picture to Zoom In

  • ARG57313 anti-CDC45 antibody WB image

    Western blot: HT-29 cell lysate stained with ARG57313 anti-CDC45 antibody.