ARG67231
anti-CDC42 antibody
anti-CDC42 antibody for ICC/IF,IHC-Formalin-fixed paraffin-embedded sections,Western blot and Drosophila,Human,Mouse,Rat
概述
| 产品描述 | Mouse Monoclonal antibody recognizes CDC42 |
|---|---|
| 反应物种 | Hu, Ms, Rat, Drosophila |
| 应用 | ICC/IF, IHC-P, WB |
| 宿主 | Mouse |
| 克隆 | Monoclonal |
| 同位型 | IgG1 |
| 靶点名称 | CDC42 |
| 偶联标记 | Un-conjugated |
| 別名 | CDC42; Cell Division Cycle 42; CDC42Hs; G25K; Cell Division Control Protein 42 Homolog; GTP Binding Protein, 25kDa; G25K GTP-Binding Protein; DJ224A6.1.1 (Cell Division Cycle 42 (GTP-Binding Protein, 25kD)); DJ224A6.1.2 (Cell Division Cycle 42 (GTP-Binding Protein, 25kD)); Cell Division Cycle 42 (GTP Binding Protein, 25kDa); Cell Division Cycle 42 (GTP-Binding Protein, 25kD); Small GTP Binding Protein CDC42; Growth-Regulating Protein; EC 3.6.5.2; TKS |
应用说明
| 应用建议 |
|
||||||||
|---|---|---|---|---|---|---|---|---|---|
| 应用说明 | * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. |
属性
| 形式 | Liquid |
|---|---|
| 纯化 | Affinity purified |
| 缓冲液 | PBS (pH 7.0), 0.025% ProClin 300 and 20% Glycerol. |
| 抗菌剂 | 0.025% ProClin 300 |
| 稳定剂 | 20% Glycerol |
| 浓度 | 0.5 mg/ml |
| 存放说明 | For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C or below. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
| 注意事项 | For laboratory research only, not for drug, diagnostic or other use. |
生物信息
| 数据库连接 | |
|---|---|
| 基因名称 | CDC42 |
| 全名 | Cell Division Cycle 42 |
| 背景介绍 | The protein encoded by this gene is a small GTPase of the Rho-subfamily, which regulates signaling pathways that control diverse cellular functions including cell morphology, migration, endocytosis and cell cycle progression. This protein is highly similar to Saccharomyces cerevisiae Cdc 42, and is able to complement the yeast cdc42-1 mutant. The product of oncogene Dbl was reported to specifically catalyze the dissociation of GDP from this protein. This protein could regulate actin polymerization through its direct binding to Neural Wiskott-Aldrich syndrome protein (N-WASP), which subsequently activates Arp2/3 complex. Alternative splicing of this gene results in multiple transcript variants. Pseudogenes of this gene have been identified on chromosomes 3, 4, 5, 7, 8 and 20. [provided by RefSeq, Apr 2013] |
| 生物功能 | Upon activation by PLEKHG4B, involved in actin cytoskeletal remodeling during epithelial cell-cell junction formation. [Uniprot] |
| 细胞定位 | Cell membrane, Cell projection, Cytoplasm, Cytoskeleton, Membrane. [Uniprot] |
| 预测分子量 | 22 kDa |
| 翻译后修饰 | Glycoprotein, Lipoprotein, Methylation, Phosphoprotein, Prenylation. [Uniprot] |
检测图片 (3) Click the Picture to Zoom In
-
ARG67231 anti-CDC42 antibody ICC/IF image
Immunofluorescence: HeLa stained with ARG67231 anti-CDC42 antibody at 1:200 dilution.
-
ARG67231 anti-CDC42 antibody WB image
Western blot: HepG2 stained with ARG67231 anti-CDC42 antibody at 1:1000 dilution.
-
ARG67231 anti-CDC42 antibody WB image
Western blot: NIH 3T3 stained with ARG67231 anti-CDC42 antibody at 1:1000 dilution.
