ARG44794
anti-CDC42 Binding Protein Kinase Beta antibody
anti-CDC42 Binding Protein Kinase Beta antibody for IHC-Formalin-fixed paraffin-embedded sections and Human
概述
| 产品描述 | Mouse Monoclonal antibody recognizes CDC42 Binding Protein Kinase Beta |
|---|---|
| 反应物种 | Hu |
| 应用 | IHC-P |
| 宿主 | Mouse |
| 克隆 | Monoclonal |
| 同位型 | IgG1 |
| 靶点名称 | CDC42 Binding Protein Kinase Beta |
| 抗原物种 | Human |
| 抗原表位 | QRDLEHSLQM EAYERRIRRL EQEKLELSRK LQESTQTVQS LHGSSRALSN SNRDKEIKKL NEEIERLKNK IADSNRLERQ LEDTVALRQE REDSTQRLRG LEKQHRVVRQ EKEELHKQLV EASERLKSQA KELKDAHQQR KLALQEFSEL NERMAELRAQ KQKVSRQLRD KEEEMEVATQ KVDAMRQEMR RAEKLRKELE AQLDDAVAEA SKERKLREHS ENFCKQMESE LEALKVKQGG RGAGATLEHQ QEISKIKSEL EKKVLFYEEE LVRREASHVL EVKNVKKEVH DSESHQLALQ KEILMLKDKL EKSKRERHNE MEEAVGTIKD |
| 偶联标记 | Un-conjugated |
| 別名 | CDC42BPB; CDC42 Binding Protein Kinase Beta; KIAA1124; MRCKB; Myotonic Dystrophy Kinase-Related CDC42-Binding Kinase Beta; Myotonic Dystrophy Protein Kinase-Like Beta; Serine/Threonine-Protein Kinase MRCK Beta; DMPK-Like Beta; CDC42BP-Beta; EC 2.7.11.1; MRCK Beta; CDC42-Binding Protein Kinase Beta (DMPK-Like); CDC42 Binding Protein Kinase Beta (DMPK-Like); CDC42-Binding Protein Kinase Beta; EC 2.7.11; CHOCNS |
应用说明
| 应用建议 |
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| 应用说明 | * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. |
属性
| 形式 | Liquid |
|---|---|
| 纯化 | Protein A purification |
| 缓冲液 | PBS with 0.09% sodium azide |
| 抗菌剂 | 0.09% sodium azide |
| 存放说明 | For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C or below. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
| 注意事项 | For laboratory research only, not for drug, diagnostic or other use. |
生物信息
| 数据库连接 |
Swiss-port # Q9Y5S2 Human Serine/threonine-protein kinase MRCK beta |
|---|---|
| 基因名称 | CDC42BPB |
| 全名 | CDC42 Binding Protein Kinase Beta |
| 背景介绍 | This gene encodes a member of the serine/threonine protein kinase family. The encoded protein contains a Cdc42/Rac-binding p21 binding domain resembling that of PAK kinase. The kinase domain of this protein is most closely related to that of myotonic dystrophy kinase-related ROK. Studies of the similar gene in rat suggested that this kinase may act as a downstream effector of Cdc42 in cytoskeletal reorganization. [provided by RefSeq, Jul 2008] |
| 生物功能 | In concert with FAM89B/LRAP25 mediates the targeting of LIMK1 to the lamellipodium resulting in its activation and subsequent phosphorylation of CFL1 which is important for lamellipodial F-actin regulation. [Uniprot] |
| 细胞定位 | Cell junction, Cell membrane, Cell projection, Cytoplasm, Membrane. [Uniprot] |
| 翻译后修饰 | Methylation, Phosphoprotein. [Uniprot] |
检测图片 (1) Click the Picture to Zoom In
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ARG44794 anti-CDC42 Binding Protein Kinase Beta antibody IHC-P image
Immunohistochemistry: Human brain stained with ARG44794 anti-CDC42 Binding Protein Kinase Beta antibody at 2.5 µg/mL dilution.
