ARG62953
anti-CD97 antibody [MEM-180]
anti-CD97 antibody [MEM-180] for Flow cytometry,Immunoprecipitation and Human
Developmental Biology antibody; Immune System antibody; Neuroscience antibody; Signaling Transduction antibody
概述
| 产品描述 | Mouse Monoclonal antibody [MEM-180] recognizes CD97 |
|---|---|
| 反应物种 | Hu |
| 应用 | FACS, IP |
| 特异性 | The clone MEM-180 recognizes an unique epitope on CD97, a 75-85 kDa surface glycoprotein of G-protein-coupled receptor family, expressed on activated B and T lymphocytes, monocytes/macrophages, dendritic cells and granulocytes. HLDA VI; WS Code BP 415 HLDA VI; WS Code NL N-L023 |
| 宿主 | Mouse |
| 克隆 | Monoclonal |
| 克隆号 | MEM-180 |
| 同位型 | IgG1 |
| 靶点名称 | CD97 |
| 抗原 | PHA-activated peripheral blood cells |
| 偶联标记 | Un-conjugated |
| 別名 | CD97; Leukocyte antigen CD97; CD97 antigen; CD antigen CD97; TM7LN1 |
应用说明
| 应用建议 |
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| 应用说明 | * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. |
属性
| 形式 | Liquid |
|---|---|
| 纯化 | Purified from ascites by protein-A affinity chromatography. |
| 纯度 | > 95% (by SDS-PAGE) |
| 缓冲液 | PBS (pH 7.4) and 15 mM Sodium azide |
| 抗菌剂 | 15 mM Sodium azide |
| 浓度 | 1 mg/ml |
| 存放说明 | For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C or below. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
| 注意事项 | For laboratory research only, not for drug, diagnostic or other use. |
生物信息
| 数据库连接 | |
|---|---|
| 基因名称 | ADGRE5 |
| 全名 | adhesion G protein-coupled receptor E5 |
| 背景介绍 | CD97 is a G-protein-coupled seven-span transmembrane adhesive receptor that is constitutively expressed on granulocytes and monocytes and rapidly upregulated on T and B cells upon activation. CD97 is produced in alternatively spliced forms and its cellular ligand is CD55 (DAF), which protects various cell types from complement-mediated damage. Interaction of CD97 on leukocytes and CD55 on vessel cells probably facilitate leukocyte activation and migration into the tissues, similarly, CD97 seems to play a role in tumour migration and invasiveness. CD97 is involved in T cell regulation and peripheral granulocyte homeostasis. |
| 生物功能 | Receptor potentially involved in both adhesion and signaling processes early after leukocyte activation. Plays an essential role in leukocyte migration (By similarity). [UniProt] |
| 研究领域 | Developmental Biology antibody; Immune System antibody; Neuroscience antibody; Signaling Transduction antibody |
| 预测分子量 | 92 kDa |
| 翻译后修饰 | Proteolytically cleaved into 2 subunits, an extracellular alpha subunit and a seven-transmembrane subunit. |
检测图片 (1) Click the Picture to Zoom In
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ARG62953 anti-CD97 antibody [MEM-180] FACS image
Flow Cytometry: Human peripheral blood stained with ARG62953 anti-CD97 antibody [MEM-180], followed by incubation with APC labelled Goat anti-Mouse secondary antibody.
