ARG42293
anti-CD89 antibody [A59] (FITC)
anti-CD89 antibody [A59] (FITC) for Flow cytometry and Human,Primates
概述
| 产品描述 | FITC-conjugated Mouse Monoclonal antibody [A59] recognizes CD89 |
|---|---|
| 反应物种 | Hu, NHuPrm |
| 应用 | FACS |
| 特异性 | The mouse monoclonal antibody A59 recognizes an extracellular epitope of CD89, a 55-100 kDa glycoprotein serving as a receptor for IgA and expressed mainly on granulocytes, monocytes and macrophages. |
| 宿主 | Mouse |
| 克隆 | Monoclonal |
| 克隆号 | A59 |
| 同位型 | IgG1, kappa |
| 靶点名称 | CD89 |
| 抗原物种 | Human |
| 抗原 | Ag8.653 myeloma cells. |
| 偶联标记 | FITC |
| 別名 | CD89; CTB-61M7.2; FcalphaRI; CD antigen CD89; Immunoglobulin alpha Fc receptor; IgA Fc receptor |
应用说明
| 应用建议 |
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| 应用说明 | * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. |
属性
| 形式 | Liquid |
|---|---|
| 纯化 | Purified |
| 缓冲液 | PBS and 15 mM Sodium azide. |
| 抗菌剂 | 15 mM Sodium azide |
| 存放说明 | Aliquot and store in the dark at 2-8°C. Keep protected from prolonged exposure to light. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
| 注意事项 | For laboratory research only, not for drug, diagnostic or other use. |
生物信息
| 数据库连接 | |
|---|---|
| 基因名称 | FCAR |
| 全名 | Fc fragment of IgA receptor |
| 背景介绍 | This gene is a member of the immunoglobulin gene superfamily and encodes a receptor for the Fc region of IgA. The receptor is a transmembrane glycoprotein present on the surface of myeloid lineage cells such as neutrophils, monocytes, macrophages, and eosinophils, where it mediates immunologic responses to pathogens. It interacts with IgA-opsonized targets and triggers several immunologic defense processes, including phagocytosis, antibody-dependent cell-mediated cytotoxicity, and stimulation of the release of inflammatory mediators. Multiple alternatively spliced transcript variants encoding different isoforms have been described for this gene. [provided by RefSeq, Jul 2008] |
| 生物功能 | Binds to the Fc region of immunoglobulins alpha. Mediates several functions including cytokine production. [UniProt] |
| 细胞定位 | Isoform A.1: Cell membrane; Single-pass type I membrane protein. Isoform A.2: Cell membrane; Single-pass type I membrane protein. Isoform A.3: Cell membrane; Single-pass type I membrane protein. Isoform B: Secreted. Isoform B-delta-S2: Secreted. [UniProt] |
| 预测分子量 | 32 kDa |
检测图片 (1) Click the Picture to Zoom In
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ARG42293 anti-CD89 antibody [A59] (FITC) FACS image
Flow Cytometry: Human peripheral blood stained with ARG42293 anti-CD89 antibody [A59] (FITC).
