ARG67261
anti-CD70 antibody [SQab30377]
anti-CD70 antibody [SQab30377] for IHC-Formalin-fixed paraffin-embedded sections and Human
概述
| 产品描述 | Rabbit Monoclonal antibody [SQab30377] recognizes CD70. |
|---|---|
| 反应物种 | Hu |
| 应用 | IHC-P |
| 宿主 | Rabbit |
| 克隆 | Monoclonal |
| 克隆号 | SQab30377 |
| 同位型 | IgG |
| 靶点名称 | CD70 |
| 抗原 | Synthetic peptide. |
| 偶联标记 | Un-conjugated |
| 別名 | CD70; CD70 Molecule; CD27-L; CD27L; CD70 Antigen; CD27 Ligand; CD27LG; TNFSF7; Tumor Necrosis Factor Ligand Superfamily Member 7; Tumor Necrosis Factor (Ligand) Superfamily, Member 7; Tumor Necrosis Factor Ligand 8A; Surface Antigen CD70; Ki-24 Antigen; TNLG8A; LPFS3 |
应用说明
| 应用建议 |
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| 应用说明 | * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. |
属性
| 形式 | Liquid |
|---|---|
| 纯化 | Affinity purification with immunogen. |
| 缓冲液 | PBS, 0.01% Sodium azide, 40% Glycerol and 0.05% BSA. |
| 抗菌剂 | 0.01% Sodium azide |
| 稳定剂 | 40% Glycerol and 0.05% BSA |
| 存放说明 | For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C or below. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
| 注意事项 | For laboratory research only, not for drug, diagnostic or other use. |
生物信息
| 数据库连接 | |
|---|---|
| 基因名称 | CD70 |
| 全名 | CD70 Molecule |
| 背景介绍 | The protein encoded by this gene is a cytokine that belongs to the tumor necrosis factor (TNF) ligand family. This cytokine is a ligand for TNFRSF27/CD27. It is a surface antigen on activated, but not on resting, T and B lymphocytes. It induces proliferation of costimulated T cells, enhances the generation of cytolytic T cells, and contributes to T cell activation. This cytokine is also reported to play a role in regulating B-cell activation, cytotoxic function of natural killer cells, and immunoglobulin sythesis. [provided by RefSeq, Jul 2008] |
| 生物功能 | The CD70-CD27 signaling pathway mediates antigen-specific T cell activation and expansion which in turn provides immune surveillance of B cells. [Uniprot] |
| 细胞定位 | Cell membrane, Membrane. [Uniprot] |
| 预测分子量 | 21 kDa |
| 翻译后修饰 | Disulfide bond, Glycoprotein. [Uniprot] |
检测图片 (1) Click the Picture to Zoom In
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ARG67261 anti-CD70 antibody [SQab30377] IHC-P image
Immunohistochemistry: Human Clear cell renal cell carcinoma stained with ARG67261 anti-CD70 antibody [SQab30377] at 1:100 dilution.
