ARG44610
anti-CD70 antibody [Ki-24] (FITC)
anti-CD70 antibody [Ki-24] (FITC) for Flow cytometry and Human
概述
| 产品描述 | FITC-conjugated Mouse Monoclonal antibody recognizes CD70 |
|---|---|
| 反应物种 | Hu |
| 应用 | FACS |
| 宿主 | Mouse |
| 克隆 | Monoclonal |
| 克隆号 | Ki-24 |
| 同位型 | IgG3 kappa |
| 靶点名称 | CD70 |
| 抗原物种 | Human |
| 偶联标记 | FITC |
| 別名 | CD70; CD70 Molecule; CD27-L; CD27L; CD70 Antigen; CD27 Ligand; CD27LG; TNFSF7; Tumor Necrosis Factor Ligand Superfamily Member 7; Tumor Necrosis Factor (Ligand) Superfamily, Member 7; Tumor Necrosis Factor Ligand 8A; Surface Antigen CD70; Ki-24 Antigen; TNLG8A; LPFS3 |
应用说明
| 应用建议 |
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| 应用说明 | * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. |
属性
| 形式 | Liquid |
|---|---|
| 纯化 | Purified antibody is conjugated with fluorescein isothiocyanate (FITC), and unconjugated antibody and free fluorochrome are removed by size-exclusion chromatography. |
| 缓冲液 | PBS (pH 7.4) and 15 mM Sodium azide |
| 抗菌剂 | 15 mM Sodium azide |
| 存放说明 | Aliquot and store in the dark at 2-8°C. Keep protected from prolonged exposure to light. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
| 注意事项 | For laboratory research only, not for drug, diagnostic or other use. |
生物信息
| 数据库连接 | |
|---|---|
| 基因名称 | CD70 |
| 全名 | CD70 Molecule |
| 背景介绍 | The protein encoded by this gene is a cytokine that belongs to the tumor necrosis factor (TNF) ligand family. This cytokine is a ligand for TNFRSF27/CD27. It is a surface antigen on activated, but not on resting, T and B lymphocytes. It induces proliferation of costimulated T cells, enhances the generation of cytolytic T cells, and contributes to T cell activation. This cytokine is also reported to play a role in regulating B-cell activation, cytotoxic function of natural killer cells, and immunoglobulin sythesis. [provided by RefSeq, Jul 2008] |
| 生物功能 | The CD70-CD27 signaling pathway mediates antigen-specific T cell activation and expansion which in turn provides immune surveillance of B cells. [UniProt] |
| 细胞定位 | Cell membrane, Membrane. [UniProt] |
| 预测分子量 | 21 kDa |
| 翻译后修饰 | Disulfide bond, Glycoprotein. [UniProt] |
检测图片 (1) Click the Picture to Zoom In
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ARG44610 anti-CD70 antibody [Ki-24] (FITC) FACS image
Flow Cytometry: HUT-78 cell stained with ARG44610 anti-CD70 antibody [Ki-24] (FITC) at 10 μl/ 100 μl dilution.
