ARG22989
anti-CD66b antibody [80H3]
anti-CD66b antibody [80H3] for Flow cytometry,Functional study,IHC-Frozen sections,Western blot and Human
概述
| 产品描述 | Mouse Monoclonal antibody [80H3] recognizes CD66b Mouse anti Human CD66b antibody, clone 80H3 reacts with the CEACAM8 or CGM6 gene product, from the carcinoembryonic gene family. The CEACAM8 gene product is called CD66b, Non-specific cross-reacting antigen NCA-95 or Carcinoembryonic antigen CGM6. CD66b is a 286 amino acid mature ~95-100 kDa GPI anchored molecule with an N-terminal 34 amino acid signal peptide and a 29 amino acid C-terminal propeptide, shed in the mature form. CD66b is expressed strongly by mature granulocytes and metamyelocytes, and weakly by bone marrow myelocytes. CD66b is not expressed by peripheral blood monocytes or lymphocytes. |
|---|---|
| 反应物种 | Hu |
| 应用 | FACS, FuncSt, IHC-Fr, WB |
| 宿主 | Mouse |
| 克隆 | Monoclonal |
| 克隆号 | 80H3 |
| 同位型 | IgG1 |
| 靶点名称 | CD66b |
| 抗原物种 | Human |
| 抗原 | Human leucocytes from individuals with CML. |
| 偶联标记 | Un-conjugated |
| 別名 | CD67; NCA-95; CD67 antigen; CGM6; CD66b; Carcinoembryonic antigen-related cell adhesion molecule 8; Carcinoembryonic antigen CGM6; Non-specific cross-reacting antigen NCA-95; CD antigen CD66b |
应用说明
| 应用建议 |
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| 应用说明 | Functional study: This product contains sodium azide, removal by dialysis is recommended prior to use in functional assays. IHC-Fr: The epitope recognised by this antibody is reported to be sensitive to formaldehyde fixation and tissue processing. Arigo recommends the use of acetone fixation for frozen sections. FACS: Use 10 µl of the suggested working dilution to label 5 x 10^5 cells or 100 µl whole blood. * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. |
属性
| 形式 | Liquid |
|---|---|
| 纯化 | Purification with Protein A. |
| 缓冲液 | PBS, 0.09% Sodium azide and 0.5% BSA |
| 抗菌剂 | 0.09% Sodium azide |
| 稳定剂 | 0.5% BSA |
| 浓度 | 1 mg/ml |
| 存放说明 | For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C or below. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
| 注意事项 | For laboratory research only, not for drug, diagnostic or other use. |
生物信息
| 数据库连接 |
Swiss-port # P31997 Human Carcinoembryonic antigen-related cell adhesion molecule 8 |
|---|---|
| 基因名称 | CEACAM8 |
| 全名 | carcinoembryonic antigen-related cell adhesion molecule 8 |
| 预测分子量 | 38 kDa |
