ARG22498
anti-CD66a + CD66c + CD66d antibody [YTH71.3]
anti-CD66a + CD66c + CD66d antibody [YTH71.3] for Flow cytometry,IHC-Frozen sections and Human,Rhesus Monkey
概述
| 产品描述 | Rat Monoclonal antibody [YTH71.3] recognizes CD66a + CD66c + CD66d This antibody recognizes 3 members of the human CD66 family, namely CD66a, CD66c and CD66d. CD66 members are expressed by human neutrophils and cells of the colon where it is down regulated in some cases of colon carcinoma (Neumaier et al. 2012). CD66a is also expressed in the human alveolar adenocarcinoma cell line A549 and may play a role in Moraxella catarrhalis induced apoptosis of pulmonary epithlial cells in diseases including COPD and emphysema (N'Guessan et al. 2007). |
|---|---|
| 反应物种 | Hu, R. Mk |
| 不反应物种 | Ms |
| 应用 | FACS, IHC-Fr |
| 宿主 | Rat |
| 克隆 | Monoclonal |
| 克隆号 | YTH71.3 |
| 同位型 | IgG2a |
| 靶点名称 | CD66a + CD66c + CD66d |
| 抗原物种 | Human |
| 抗原 | Human lymphocytes |
| 偶联标记 | Un-conjugated |
| 別名 | Normal cross-reacting antigen; Carcinoembryonic antigen-related cell adhesion molecule 6; CEAL; CD66c; CD antigen CD66c; NCA; Non-specific crossreacting antigen |
应用说明
| 应用建议 |
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| 应用说明 | FACS: Use 10ul of the suggested working dilution to label 10^6 cells in 100ul. * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. |
属性
| 形式 | Liquid |
|---|---|
| 纯化 | Purification with Protein G. |
| 缓冲液 | PBS and 0.09% Sodium azide |
| 抗菌剂 | 0.09% Sodium azide |
| 浓度 | 1 mg/ml |
| 存放说明 | For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C or below. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
| 注意事项 | For laboratory research only, not for drug, diagnostic or other use. |
生物信息
| 数据库连接 |
Swiss-port # P40199 Human Carcinoembryonic antigen-related cell adhesion molecule 6 |
|---|---|
| 基因名称 | CEACAM6 |
| 全名 | carcinoembryonic antigen-related cell adhesion molecule 6 (non-specific cross reacting antigen) |
| 背景介绍 | This gene encodes a protein that belongs to the carcinoembryonic antigen (CEA) family whose members are glycosyl phosphatidyl inositol (GPI) anchored cell surface glycoproteins. Members of this family play a role in cell adhesion and are widely used as tumor markers in serum immunoassay determinations of carcinoma. This gene affects the sensitivity of tumor cells to adenovirus infection. The protein encoded by this gene acts as a receptor for adherent-invasive E. coli adhesion to the surface of ileal epithelial cells in patients with Crohn's disease. This gene is clustered with genes and pseudogenes of the cell adhesion molecules subgroup of the CEA family on chromosome 19. [provided by RefSeq, Apr 2014] |
| 预测分子量 | 37 kDa |
检测图片 (1) Click the Picture to Zoom In
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ARG22498 anti-CD66a + CD66c + CD66d antibody [YTH71.3] FACS image
Flow Cytometry: Human peripheral blood granulocytes stained with ARG22498 anti-CD66a + CD66c + CD66d antibody [YTH71.3].
