ARG62908

anti-CD62L / L-Selectin antibody [IVA94]

Datasheet

订购信息

包装

价格 (USD)

100 μg

399

arigo in CHINA:
恩瑞科生物
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概述

产品描述	Mouse Monoclonal antibody [IVA94] recognizes CD62L / L-Selectin
反应物种	Bov
应用	FACS, ICC/IF, IP
特异性	The clone IVA94 reacts with CD62L antigen (bovine). CD62L (L-selectin) is a 74-95 kDa single chain type I glycoprotein expressed on most peripheral blood B lymphocytes, T lymphocytes, monocytes and granulocytes; it is also present on a subset of NK cells and certain hematopoietic malignant cells.
宿主	Mouse
克隆	Monoclonal
克隆号	IVA94
同位型	IgG1
靶点名称	CD62L / L-Selectin
抗原	Bovine leukocytes.
偶联标记	Un-conjugated
別名	Leukocyte surface antigen Leu-8; Leukocyte adhesion molecule 1; CD antigen CD62L; PLNHR; LSEL; CD62L; Leukocyte-endothelial cell adhesion molecule 1; L-selectin; LAM1; LNHR; TQ1; CD62 antigen-like family member L; gp90-MEL; Lymph node homing receptor; LYAM1; LECAM1; LEU8; LAM-1

应用说明

应用建议

应用说明

* The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist.

属性

形式	Liquid
纯化	Purified from ascites by protein-A affinity chromatography.
纯度	> 95% (by SDS-PAGE)
缓冲液	PBS (pH 7.4) and 15 mM Sodium azide
抗菌剂	15 mM Sodium azide
浓度	1 mg/ml
存放说明	For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C or below. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use.
注意事项	For laboratory research only, not for drug, diagnostic or other use.

生物信息

数据库连接	GeneID: 281485 Bovine SELL Swiss-port # P98131 Bovine L-selectin
基因名称	SELL
全名	selectin L
背景介绍	This gene encodes a cell surface adhesion molecule that belongs to a family of adhesion/homing receptors. The encoded protein contains a C-type lectin-like domain, a calcium-binding epidermal growth factor-like domain, and two short complement-like repeats. The gene product is required for binding and subsequent rolling of leucocytes on endothelial cells, facilitating their migration into secondary lymphoid organs and inflammation sites. Single-nucleotide polymorphisms in this gene have been associated with various diseases including immunoglobulin A nephropathy. Alternatively spliced transcript variants have been found for this gene. [provided by RefSeq, Oct 2009]
生物功能	Cell surface adhesion protein. Mediates the adherence of lymphocytes to endothelial cells of high endothelial venules in peripheral lymph nodes. Promotes initial tethering and rolling of leukocytes in endothelia (By similarity). [UniProt]
研究领域	Cell Biology and Cellular Response antibody; Developmental Biology antibody; Immune System antibody; Signaling Transduction antibody
预测分子量	42 kDa

检测图片 (3) Click the Picture to Zoom In

ARG62908 anti-CD62L / L-Selectin antibody [IVA94] ICC/IF image

Immunofluorescence: Acetone / methanol-fixed Bovine peripheral blood (lymphocyte-enriched suspension) stained with ARG62908 anti-CD62L / L-Selectin antibody [IVA94] (green), DAPI (blue) for nuclear staining.
ARG62908 anti-CD62L / L-Selectin antibody [IVA94] FACS image

Flow Cytometry: Separation of bovine CD62L positive lymphocytes (red-filled) from CD62L negative lymphocytes (black-dashed). Bovine peripheral whole blood stained with ARG62908 anti-CD62L / L-Selectin antibody [IVA94] at 1 µg/ml dilution, followed by APC-conjugated Goat anti-Mouse antibody.
ARG62908 anti-CD62L / L-Selectin antibody [IVA94] FACS image

Flow Cytometry: Bovine peripheral whole blood stained with ARG62908 anti-CD62L / L-Selectin antibody [IVA94] at 1 µg/ml dilution, followed by APC-conjugated Goat anti-Mouse antibody.