ARG20960
anti-CD62E / E-Selectin antibody [1.2B6] (APC)
anti-CD62E / E-Selectin antibody [1.2B6] (APC) for Blocking,ELISA,Flow cytometry,ICC/IF,IHC-Frozen sections,Western blot and Human,Pig
概述
| 产品描述 | APC-conjugated Mouse Monoclonal antibody [1.2B6] recognizes CD62E / E-Selectin |
|---|---|
| 反应物种 | Hu, Pig |
| 应用 | BL, ELISA, FACS, ICC/IF, IHC-Fr, WB |
| 特异性 | Human CD62E & CD62P/Porcine CD62E. The clone 1.2B6 recognizes a common epitope shared by CD62E and CD62P. |
| 宿主 | Mouse |
| 克隆 | Monoclonal |
| 克隆号 | 1.2B6 |
| 同位型 | IgG1, kappa |
| 靶点名称 | CD62E / E-Selectin |
| 抗原物种 | Human |
| 抗原 | TNF stimulated human endothelial cells |
| 偶联标记 | APC |
| 別名 | E-selectin; CD62E; ELAM-1; ELAM1; CD antigen CD62E; ELAM; Endothelial leukocyte adhesion molecule 1; Leukocyte-endothelial cell adhesion molecule 2; ESEL; LECAM2; CD62 antigen-like family member E |
应用说明
| 应用建议 |
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| 应用说明 | WB: Under non-reducing condition. * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. |
属性
| 形式 | Liquid |
|---|---|
| 缓冲液 | PBS, 0.1% Sodium azide and Sucrose. |
| 抗菌剂 | 0.1% Sodium azide |
| 稳定剂 | Sucrose |
| 存放说明 | Aliquot and store in the dark at 2-8°C. Keep protected from prolonged exposure to light. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
| 注意事项 | For laboratory research only, not for drug, diagnostic or other use. |
生物信息
| 数据库连接 | |
|---|---|
| 基因名称 | SELE |
| 全名 | selectin E |
| 背景介绍 | The protein encoded by this gene is found in cytokine-stimulated endothelial cells and is thought to be responsible for the accumulation of blood leukocytes at sites of inflammation by mediating the adhesion of cells to the vascular lining. It exhibits structural features such as the presence of lectin- and EGF-like domains followed by short consensus repeat (SCR) domains that contain 6 conserved cysteine residues. These proteins are part of the selectin family of cell adhesion molecules. Adhesion molecules participate in the interaction between leukocytes and the endothelium and appear to be involved in the pathogenesis of atherosclerosis. [provided by RefSeq, Jul 2008] |
| 生物功能 | Cell-surface glycoprotein having a role in immunoadhesion. Mediates in the adhesion of blood neutrophils in cytokine-activated endothelium through interaction with PSGL1/SELPLG. May have a role in capillary morphogenesis. [UniProt] |
| 预测分子量 | 67 kDa |
