ARG62426
anti-CD6 antibody [SPV-L14]
anti-CD6 antibody [SPV-L14] for ELISA,Flow cytometry,ICC/IF,IHC-Formalin-fixed paraffin-embedded sections,Immunoprecipitation,Western blot and Human,Mouse
Developmental Biology antibody; Immune System antibody
概述
| 产品描述 | Mouse Monoclonal antibody [SPV-L14] recognizes CD6 |
|---|---|
| 反应物种 | Hu, Ms |
| 应用 | ELISA, FACS, ICC/IF, IHC-P, IP, WB |
| 宿主 | Mouse |
| 克隆 | Monoclonal |
| 克隆号 | SPV-L14 |
| 同位型 | IgG1 |
| 靶点名称 | CD6 |
| 抗原物种 | Human |
| 抗原 | Anti-CD6 antibody was raised against CD8+ cytotoxic T-cell clone |
| 偶联标记 | Un-conjugated |
| 別名 | CD antigen CD6; TP120; T-cell differentiation antigen CD6; T12 |
应用说明
| 应用说明 | IHC: 0.5-1.0 ug/ml FACS: 0.5-1.0 ug antibody/million cells ICC/IF: 0.5-1.0 ug/ml IP: 0.5-1.0 ug antibody/500 ug protein lysate * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. |
|---|
属性
| 形式 | Liquid |
|---|---|
| 纯化 | Protein A/G purified |
| 缓冲液 | 1X PBS buffer with < 0.1% sodium azide. |
| 抗菌剂 | < 0.1% sodium azide. |
| 浓度 | 2 mg/ml |
| 存放说明 | For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C or below. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
| 注意事项 | For laboratory research only, not for drug, diagnostic or other use. |
生物信息
| 数据库连接 |
Swiss-port # P30203 Human T-cell differentiation antigen CD6 Swiss-port # Q61003 Mouse T-cell differentiation antigen CD6 |
|---|---|
| 基因名称 | CD6 |
| 全名 | CD6 molecule |
| 背景介绍 | CD6 is a type I transmembrane glycoprotein that contains a 24-amino acid signal sequence, three extracellular “scavenger receptor cysteine-rich” (SRCR) domains, a membrane-spanning domain and a 44-amino acid cytoplasmic domain. The CD6 glycoprotein is tyrosine phosphorylated during TCR-mediated T cell activation. CD6 shows significant homology to CD5. CD6 is present on mature thymocytes, peripheral T cells and a subset of B cells. Antibodies to CD6 are used to deplete T cells from bone marrow transplants to prevent graft versus host disease. |
| 生物功能 | Involved in cell adhesion. Binds to CD166. [UniProt] |
| 研究领域 | Developmental Biology antibody; Immune System antibody |
| 预测分子量 | 72 kDa |
| 翻译后修饰 | After T-cell activation, becomes hyperphosphorylated on Ser and Thr residues and phosphorylated on Tyr residues. Glycosylated. |
