ARG65850
anti-CD6 antibody [MRC OX-52] (FITC)
anti-CD6 antibody [MRC OX-52] (FITC) for Flow cytometry and Rat
概述
| 产品描述 | FITC-conjugated Mouse Monoclonal antibody [MRC OX-52] recognizes CD6 |
|---|---|
| 反应物种 | Rat |
| 应用 | FACS |
| 特异性 | This monoclonal antibody immunoprecipitates a two chain structure (95, 120 kDa) largely restricted to T lymphocytes and thymocytes. This clone does not inhibit the allogeneic mixed leukocyte response, nor does it inhibit T cytotoxic effector cell function. |
| 宿主 | Mouse |
| 克隆 | Monoclonal |
| 克隆号 | MRC OX-52 |
| 同位型 | IgG2a |
| 靶点名称 | CD6 |
| 抗原物种 | Rat |
| 抗原 | Rat CD6 |
| 偶联标记 | FITC |
| 別名 | CD antigen CD6; TP120; T-cell differentiation antigen CD6; T12 |
应用说明
| 应用建议 |
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| 应用说明 | * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. |
属性
| 形式 | Liquid |
|---|---|
| 纯化 | Purified. |
| 缓冲液 | PBS (pH 7.2), 0.09% Sodium azide and 1% BSA. |
| 抗菌剂 | 0.09% Sodium azide |
| 稳定剂 | 1% BSA |
| 存放说明 | Aliquot and store in the dark at 2-8°C. Keep protected from prolonged exposure to light. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
| 注意事项 | For laboratory research only, not for drug, diagnostic or other use. |
生物信息
| 基因名称 | Cd6 |
|---|---|
| 全名 | Cd6 molecule |
| 背景介绍 | This gene encodes a protein found on the outer membrane of T-lymphocytes as well as some other immune cells. The encoded protein contains three scavenger receptor cysteine-rich (SRCR) domains and a binding site for an activated leukocyte cell adhesion molecule. The gene product is important for continuation of T cell activation. This gene may be associated with susceptibility to multiple sclerosis (PMID: 19525953, 21849685). Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Dec 2011] |
| 生物功能 | Involved in cell adhesion. Binds to CD166. [UniProt] |
| 预测分子量 | 72 kDa |
| 翻译后修饰 | After T-cell activation, becomes hyperphosphorylated on Ser and Thr residues and phosphorylated on Tyr residues. Glycosylated. |
