ARG42280
anti-CD5 antibody [L17F12] (PerCP)
anti-CD5 antibody [L17F12] (PerCP) for Flow cytometry and Human
概述
| 产品描述 | PerCP-conjugated Mouse Monoclonal antibody [L17F12] recognizes CD5 |
|---|---|
| 反应物种 | Hu |
| 应用 | FACS |
| 特异性 | The mouse monoclonal antibody L17F12 reacts with an extracellular epitope of CD5, a 67kDa single-chain transmembrane glycoprotein expressed on mature T lymphocytes, most of thymocytes and B lymphocytes subset (B-1a lymphocytes). |
| 宿主 | Mouse |
| 克隆 | Monoclonal |
| 克隆号 | L17F12 |
| 同位型 | IgG2a, kappa |
| 靶点名称 | CD5 |
| 抗原物种 | Human |
| 抗原 | Human acute lymphoblastic leukemia (ALL) T cells. |
| 偶联标记 | PerCP |
| 別名 | CD antigen CD5; Lymphocyte antigen T1/Leu-1; LEU1; T-cell surface glycoprotein CD5; T1 |
应用说明
| 应用建议 |
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| 应用说明 | * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. |
属性
| 形式 | Liquid |
|---|---|
| 纯化 | Purified |
| 缓冲液 | PBS and 15 mM Sodium azide. |
| 抗菌剂 | 15 mM Sodium azide |
| 存放说明 | Aliquot and store in the dark at 2-8°C. Keep protected from prolonged exposure to light. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
| 注意事项 | For laboratory research only, not for drug, diagnostic or other use. |
生物信息
| 数据库连接 | |
|---|---|
| 基因名称 | CD5 |
| 全名 | CD5 molecule |
| 背景介绍 | This gene encodes a member of the scavenger receptor cysteine-rich (SRCR) superfamily. Members of this family are secreted or membrane-anchored proteins mainly found in cells associated with the immune system. This protein is a type-I transmembrane glycoprotein found on the surface of thymocytes, T lymphocytes and a subset of B lymphocytes. The encoded protein contains three SRCR domains and may act as a receptor to regulate T-cell proliferation. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Oct 2016] |
| 生物功能 | May act as a receptor in regulating T-cell proliferation. [UniProt] |
| 细胞定位 | Cell membrane; Single-pass type I membrane protein. [UniProt] |
| 预测分子量 | 55 kDa |
| 翻译后修饰 | Phosphorylated on tyrosine residues by LYN; this creates binding sites for PTPN6/SHP-1. [UniProt] |
检测图片 (1) Click the Picture to Zoom In
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ARG42280 anti-CD5 antibody [L17F12] (PerCP) FACS image
Flow Cytometry: Human peripheral blood cells stained with ARG42280 anti-CD5 antibody [L17F12] (PerCP).
