ARG42503
anti-CD5 antibody
anti-CD5 antibody for IHC-Formalin-fixed paraffin-embedded sections,IHC-Frozen sections,Western blot and Dog,Human,Monkey,Mouse,Rat
概述
产品描述 | Goat Polyclonal antibody recognizes CD5 |
---|---|
反应物种 | Hu, Ms, Rat, Dog, Mk |
应用 | IHC-Fr, IHC-P, WB |
宿主 | Goat |
克隆 | Polyclonal |
同位型 | IgG |
靶点名称 | CD5 |
抗原物种 | Human |
抗原 | Recombinant peptide within aa. 105-210 of Human CD5. |
偶联标记 | Un-conjugated |
別名 | CD antigen CD5; Lymphocyte antigen T1/Leu-1; LEU1; T-cell surface glycoprotein CD5; T1 |
应用说明
应用建议 |
|
||||||||
---|---|---|---|---|---|---|---|---|---|
应用说明 | * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. | ||||||||
阳性对照 | PBMCs | ||||||||
实际分子量 | ~ 70 kDa |
属性
形式 | Liquid |
---|---|
纯化 | Affinity purification with immunogen. |
缓冲液 | PBS, 0.05% Sodium azide and 20% Glycerol. |
抗菌剂 | 0.05% Sodium azide |
稳定剂 | 20% Glycerol |
浓度 | 3 mg/ml |
存放说明 | For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
注意事项 | For laboratory research only, not for drug, diagnostic or other use. |
生物信息
数据库连接 | |
---|---|
基因名称 | CD5 |
全名 | CD5 molecule |
背景介绍 | This gene encodes a member of the scavenger receptor cysteine-rich (SRCR) superfamily. Members of this family are secreted or membrane-anchored proteins mainly found in cells associated with the immune system. This protein is a type-I transmembrane glycoprotein found on the surface of thymocytes, T lymphocytes and a subset of B lymphocytes. The encoded protein contains three SRCR domains and may act as a receptor to regulate T-cell proliferation. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Oct 2016] |
生物功能 | May act as a receptor in regulating T-cell proliferation. [UniProt] |
细胞定位 | Cell membrane; Single-pass type I membrane protein. [UniProt] |
预测分子量 | 55 kDa |
翻译后修饰 | Phosphorylated on tyrosine residues by LYN; this creates binding sites for PTPN6/SHP-1. [UniProt] |
检测图片 (3) Click the Picture to Zoom In
-
ARG42503 anti-CD5 antibody IHC-P image
Immunohistochemistry: Human appendix stained with ARG42503 anti-CD5 antibody at 1:750 dilution.
-
ARG42503 anti-CD5 antibody WB image
Western blot: 50 µg of PBMCs stained with ARG42503 anti-CD5 antibody at 1:1000 dilution.
-
ARG42503 anti-CD5 antibody IHC-P image
Immunohistochemistry: Mouse spleen stained with ARG42503 anti-CD5 antibody at 1:750 dilution.