ARG22911
anti-CD42a antibody [GRP-P] (FITC)
anti-CD42a antibody [GRP-P] (FITC) for Flow cytometry and Human,Dog
概述
| 产品描述 | FITC-conjugated Mouse Monoclonal antibody [GRP-P] recognizes CD42a Mouse anti Human CD42a antibody, clone GRP-P recognizes the platelet GPIX glycoprotein, a 23kDa surface marker expressed by platelets and megakaryocytes. Platelet GPIX is also known as CD42a.The CD42 complex is the major platelet receptor for von Willebrand factor. |
|---|---|
| 反应物种 | Hu, Dog |
| 应用 | FACS |
| 宿主 | Mouse |
| 克隆 | Monoclonal |
| 克隆号 | GRP-P |
| 同位型 | IgG1 |
| 靶点名称 | CD42a |
| 抗原物种 | Human |
| 抗原 | Human red blood cells and platelets. |
| 偶联标记 | FITC |
| 別名 | Glycoprotein 9; CD antigen CD42a; CD42a; GPIX; GP-IX; Platelet glycoprotein IX |
应用说明
| 应用建议 |
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| 应用说明 | FACS: Use 10 µl of the suggested working dilution to label 10^6 cells or 100 µl whole blood. * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. |
属性
| 形式 | Liquid |
|---|---|
| 纯化 | Purification with Protein G. |
| 缓冲液 | PBS, 0.09% Sodium azide and 1% BSA |
| 抗菌剂 | 0.09% Sodium azide |
| 稳定剂 | 1% BSA |
| 浓度 | 0.1 mg/ml |
| 存放说明 | Aliquot and store in the dark at 2-8°C. Keep protected from prolonged exposure to light. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
| 注意事项 | For laboratory research only, not for drug, diagnostic or other use. |
生物信息
| 数据库连接 | |
|---|---|
| 基因名称 | GP9 |
| 全名 | glycoprotein IX (platelet) |
| 背景介绍 | This gene encodes a small membrane glycoprotein found on the surface of human platelets. It forms a 1-to-1 noncovalent complex with glycoprotein Ib, a platelet surface membrane glycoprotein complex that functions as a receptor for von Willebrand factor. The complete receptor complex includes noncovalent association of the alpha and beta subunits with the protein encoded by this gene and platelet glycoprotein V. Defects in this gene are a cause of Bernard-Soulier syndrome, also known as giant platelet disease. These patients have unusually large platelets and have a clinical bleeding tendency. [provided by RefSeq, Oct 2008] |
| 生物功能 | The GPIb-V-IX complex functions as the vWF receptor and mediates vWF-dependent platelet adhesion to blood vessels. The adhesion of platelets to injured vascular surfaces in the arterial circulation is a critical initiating event in hemostasis. GP-IX may provide for membrane insertion and orientation of GP-Ib. [UniProt] |
| 预测分子量 | 19 kDa |
检测图片 (1) Click the Picture to Zoom In
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ARG22911 anti-CD42a antibody [GRP-P] (FITC) FACS image
Flow Cytometry: Human peripheral blood platelets stained with ARG22911 anti-CD42a antibody [GRP-P] (FITC).
