ARG42297
anti-CD42a antibody [GR-P] (APC)
anti-CD42a antibody [GR-P] (APC) for Flow cytometry and Human,Dog
概述
| 产品描述 | APC-conjugated Mouse Monoclonal antibody [GR-P] recognizes CD42a |
|---|---|
| 反应物种 | Hu, Dog |
| 应用 | FACS |
| 特异性 | The mouse monoclonal antibody GR-P (also known as GRP-P) recognizes an extracellular epitope of CD42a (glycoprotein 9), a 22 kDa transmembrane protein constitutively expressed on megakaryocytes and platelets. |
| 宿主 | Mouse |
| 克隆 | Monoclonal |
| 克隆号 | GR-P |
| 同位型 | IgG1 |
| 靶点名称 | CD42a |
| 抗原物种 | Human |
| 抗原 | Human acute lymphoblastic leukemia cells. |
| 偶联标记 | APC |
| 別名 | Glycoprotein 9; CD antigen CD42a; CD42a; GPIX; GP-IX; Platelet glycoprotein IX |
应用说明
| 应用建议 |
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| 应用说明 | * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. |
属性
| 形式 | Liquid |
|---|---|
| 纯化 | Purified |
| 缓冲液 | PBS and 15 mM Sodium azide. |
| 抗菌剂 | 15 mM Sodium azide |
| 存放说明 | Aliquot and store in the dark at 2-8°C. Keep protected from prolonged exposure to light. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
| 注意事项 | For laboratory research only, not for drug, diagnostic or other use. |
生物信息
| 数据库连接 | |
|---|---|
| 基因名称 | GP9 |
| 全名 | glycoprotein IX (platelet) |
| 背景介绍 | This gene encodes a small membrane glycoprotein found on the surface of human platelets. It forms a 1-to-1 noncovalent complex with glycoprotein Ib, a platelet surface membrane glycoprotein complex that functions as a receptor for von Willebrand factor. The complete receptor complex includes noncovalent association of the alpha and beta subunits with the protein encoded by this gene and platelet glycoprotein V. Defects in this gene are a cause of Bernard-Soulier syndrome, also known as giant platelet disease. These patients have unusually large platelets and have a clinical bleeding tendency. [provided by RefSeq, Oct 2008] |
| 生物功能 | The GPIb-V-IX complex functions as the vWF receptor and mediates vWF-dependent platelet adhesion to blood vessels. The adhesion of platelets to injured vascular surfaces in the arterial circulation is a critical initiating event in hemostasis. GP-IX may provide for membrane insertion and orientation of GP-Ib. [UniProt] |
| 细胞定位 | Membrane; Single-pass type I membrane protein. [UniProt] |
| 预测分子量 | 19 kDa |
检测图片 (2) Click the Picture to Zoom In
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ARG42297 anti-CD42a antibody [GR-P] (APC) FACS image
Flow Cytometry: Human peripheral whole blood stained with ARG42297 anti-CD42a antibody [GR-P] (APC) at 10 µl / 100 µl of peripheral whole blood.
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ARG42297 anti-CD42a antibody [GR-P] (APC) FACS image
Flow Cytometry: Separation of Human thrombocytes (red-filled) from Human neutrophil granulocytes (black-dashed). Human peripheral whole blood stained with ARG42297 anti-CD42a antibody [GR-P] (APC) at 10 µl / 100 µl of peripheral whole blood.
