ARG21295

anti-CD4 antibody [RFT4]

anti-CD4 antibody [RFT4] for Flow cytometry,IHC-Frozen sections,ICC/IF,Western blot and Human

概述

产品描述 Mouse Monoclonal antibody [RFT4] recognizes CD4
反应物种 Hu
应用 FACS, ICC/IF, IHC-Fr, WB
特异性 Human CD4.
宿主 Mouse
克隆 Monoclonal
克隆号 RFT4
同位型 IgG1κ
靶点名称 CD4
抗原物种 Human
抗原 Thymocytes and E-rosetted lymphocytes
偶联标记 Un-conjugated
全名 CD4 molecule
別名 CD4mut; CD antigen CD4; T-cell surface glycoprotein CD4; T-cell surface antigen T4/Leu-3

应用说明

应用建议
应用 推荐稀释比
FACS< 1 µg/10^6 cells
ICC/IFAssay-dependent
IHC-FrAssay-dependent
WBAssay-dependent
应用说明 * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist.

属性

形式 Liquid
缓冲液 BBS (pH 8.2)
浓度 0.1 mg/ml
存放说明 For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use.
注意事项 For laboratory research only, not for drug, diagnostic or other use.

生物信息

数据库连接

GeneID: 920 Human CD4

Swiss-port # P01730 Human T-cell surface glycoprotein CD4

基因名称 CD4
基因全名 CD4 molecule
背景介绍 This gene encodes a membrane glycoprotein of T lymphocytes that interacts with major histocompatibility complex class II antigenes and is also a receptor for the human immunodeficiency virus. This gene is expressed not only in T lymphocytes, but also in B cells, macrophages, and granulocytes. It is also expressed in specific regions of the brain. The protein functions to initiate or augment the early phase of T-cell activation, and may function as an important mediator of indirect neuronal damage in infectious and immune-mediated diseases of the central nervous system. Multiple alternatively spliced transcript variants encoding different isoforms have been identified in this gene. [provided by RefSeq, Aug 2010]
生物功能 Accessory protein for MHC class-II antigen/T-cell receptor interaction. May regulate T-cell activation. Induces the aggregation of lipid rafts. [UniProt]
产品亮点 Related products:
CD4 antibodies; CD4 ELISA Kits; CD4 Duos / Panels; Anti-Mouse IgG secondary antibodies;
Related news:
Lymphoma
翻译后修饰 Palmitoylation and association with LCK contribute to the enrichment of CD4 in lipid rafts.