ARG44738
anti-CD328 / Siglec 7 antibody
anti-CD328 / Siglec 7 antibody for Immunoprecipitation,Western blot and Human
概述
| 产品描述 | Mouse Monoclonal antibody recognizes CD328 / Siglec 7 |
|---|---|
| 反应物种 | Hu |
| 应用 | IP, WB |
| 宿主 | Mouse |
| 克隆 | Monoclonal |
| 同位型 | IgG1 |
| 靶点名称 | CD328 / Siglec 7 |
| 抗原物种 | Human |
| 偶联标记 | Un-conjugated |
| 別名 | QA79 membrane protein; p75; CD antigen CD328; SIGLEC19P; Adhesion inhibitory receptor molecule 1; SIGLECP2; Sialic acid-binding Ig-like lectin 7; SIGLEC-7; p75/AIRM1; CDw328; Siglec-7; AIRM-1; CD328; AIRM1; D-siglec; QA79 |
应用说明
| 应用建议 |
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| 应用说明 | * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. |
属性
| 形式 | Liquid |
|---|---|
| 纯化 | Protein A purification |
| 缓冲液 | PBS with 0.09% sodium azide |
| 存放说明 | For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C or below. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
| 注意事项 | For laboratory research only, not for drug, diagnostic or other use. |
生物信息
| 数据库连接 |
Swiss-port # Q9Y286 Human Sialic acid-binding Ig-like lectin 7 |
|---|---|
| 基因名称 | SIGLEC7 |
| 全名 | sialic acid binding Ig-like lectin 7 |
| 生物功能 | Putative adhesion molecule that mediates sialic-acid dependent binding to cells. Preferentially binds to alpha-2,3- and alpha-2,6-linked sialic acid. Also binds disialogangliosides (disialogalactosyl globoside, disialyl lactotetraosylceramide and disialyl GalNAc lactotetraoslylceramide). The sialic acid recognition site may be masked by cis interactions with sialic acids on the same cell surface. In the immune response, may act as an inhibitory receptor upon ligand induced tyrosine phosphorylation by recruiting cytoplasmic phosphatase(s) via their SH2 domain(s) that block signal transduction through dephosphorylation of signaling molecules. Mediates inhibition of natural killer cells cytotoxicity. May play a role in hemopoiesis. Inhibits differentiation of CD34+ cell precursors towards myelomonocytic cell lineage and proliferation of leukemic myeloid cells (in vitro). [UniProt] |
| 细胞定位 | Membrane; Single-pass type I membrane protein. [UniProt] |
| 预测分子量 | 51 kDa |
| 翻译后修饰 | Tyrosine phosphorylated. [UniProt] |
检测图片 (2) Click the Picture to Zoom In
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ARG44738 anti-CD328 / Siglec 7 antibody WB image
Western blot: HL60 stained with ARG44738 anti-CD328 / Siglec 7 antibody at 1 µg/mL dilution.
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ARG44738 anti-CD328 / Siglec 7 antibody IP image
Immunoprecipitation: HL60 lysate immunoprecipitated with 2.5 µg of ARG44738 anti-CD328 / Siglec 7 antibody.
